RESUMEN

The structure of fermentation product A 19009 was reinvestigated by 13C and 1H NMR spectroscopy and established by independent synthesis to be N2-L-alanyl-N3-fumaramoyl-L-2,3-diaminopropanoic acid (2), i.e. a structure isomeric with the originally proposed structure 1. In contrast to 1 which also was synthesized, 2 has a very low activity against Trichomonas vaginalis.

Asunto(s)

Antibacterianos/aislamiento & purificación , Péptidos , Dipéptidos/aislamiento & purificación , Concentración de Iones de Hidrógeno , Indicadores y Reactivos , Espectroscopía de Resonancia Magnética , Streptomyces/crecimiento & desarrollo