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This study followed up 92 children at ages 6-7 first studied as one-year-olds in order to determine differences in the developmental outcome of the offspring of employed as compared to "stay at home" mothers. The developmental domain evaluated in the 6-7 year old children was peer competence, rated by laboratory play and child psychological test instruments. Mothers' reports of children's behavioral pathology at age 6-7 correlated with a higher number of maternal work hours during the infant's first year, but the children did better during overall play situations. Age 1 attachment ratings better predicted free play social competence for the entire sample than did maternal hours of work absence, but girls accounted for statistical significance. Maternal sensitivity from infancy was associated with maternal reports of (low) problem behaviors; however, regression analyses did not support the hypothesis that relations between either work status or attachment and current problem behaviors were mediated by early maternal sensitivity.

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We suggested that antepartum maternal metabolism may affect later cognitive and behavioral function of progeny by impacting on developing brain cells in utero. This study reports on the observed relationships between serial characterizations of maternal fuels during pregnancy and Brazelton neonatal behavioral assessment scale ratings of offspring from 73 well-controlled pregestational diabetic patients, 112 gestational diabetic patients, and 24 nondiabetic patients. After controlling for the effects of premature birth on the Brazelton neonatal behavioral assessment scale, significant correlations were found between second- and third-trimester glycemic regulation (hemoglobin A1c and fasting plasma glucose levels) and three of four newborn behavioral dimensions of the Brazelton neonatal behavioral assessment scale. In each case, as maternal glucose increased, the newborns' Brazelton neonatal behavioral assessment scale responses were poor. Results were not substantially different when gestational and pregestational diabetic patients were analyzed separately, nor can they be attributed to various perinatal events (neonatal asphyxia, hypoglycemia) or differences in socioeconomic status or ethnicity. The presence of fuel-related neurobehavioral deficits in neonates of diabetic mothers suggests that such infants start their interactions with care givers from a modified base.

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In summary reviews and empirical research, investigators have suggested that attachment classifications derived from the Ainsworth Strange Situation may reflect variations along dimensions of temperament as well as, or perhaps instead of, individual differences with respect to infant-mother attachments. In this study, relations between temperament dimensions from the Infant Temperament Questionnaire (Revised) and Strange Situation behaviors were evaluated. Relations between the behavioral style scores and the categories of attachment quality were also tested. The hypothesis that temperamental difficulty would be related to negative emotionality, as indexed by infant distress during separation (but not during the reunions), was tested and supported. Neither the behavioral style dimensions nor the temperamental diagnoses (e.g., "easy" vs. "difficult") were associated significantly with attachment classifications. The results are consistent with previous findings that temperament measures do not predict attachment security. Nevertheless, certain behaviors indexing negative emotionality that may be observed in the context of the Strange Situation are related to temperamental variability.

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Freud (1905, 1917, 1937) throughout his lifetime sought empirical scientific confirmation of the validity of his discoveries. In pursuit of this goal, he persistently emphasized the importance of establishing agreement between analytic reconstructions and the results of naturalistic child observation. The same objective lead Lichtenberg (1983), Emde (1981, 1985), and Stern (1985) to produce detailed evaluations of the impact of infant research findings on analytic developmental propositions. The present paper examines the relation among clinical reconstructions from an analysis developed through transference interpretations, empirical observations originating in the analytic patient's daughter's psychotherapy, and the results of empirical infant research that was being concurrently conducted by two of the authors. The findings from the clinical analysis of the mother, the psychotherapy of the daughter, and empirical infant research all converged on the same larger causative factor for the daughter's psychopathology--a type of maternal deprivation. Such a confluence of different sources of evidence, each identified by a different method of investigation, provides one kind of validation for psychoanalytic reconstructions, making it possible to provide that "satisfactory degree of certainty" which Freud (1937) called for in the attempt to integrate the patient's "psychic truth" with "actual" or historical truth.

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Recent reports have suggested that day-care experience initiated prior to 12 months of age is associated with increased proportions of infants whose attachment to mother is classified as "insecure-avoidant." However, reviewers have questioned the generality of these findings, noting that samples in which associations between early day-care experience and avoidant attachment patterns have been reported come from high-risk populations, and/or that the infants' day-care settings may not have been of high quality. In the present study, effects of maternal absences on infant-mother attachment quality were assessed in a low-risk, middle-class sample (N = 110). In all instances, substitute care had been initiated at least 4 months prior to the infant's first birthday and was provided in the infant's home by a person unrelated to the baby. Infants were assessed using the Ainsworth Strange Situation when they were 12-13 months of age. Analyses indicated that a significantly greater proportion of infants whose mothers worked outside the home (N = 54) were assigned to the category "insecure-avoidant" as compared to infants whose mothers remained in the home (N = 56) throughout the first year of life. Analyses of demographic and psychological data available for the sample indicated that this relation is dependent upon maternal parity (primi- vs. multiparous mother). The association between attachment quality and work status was significant only for firstborn children of full-time working mothers. The results are interpreted as evidence that the repeated daily separations experienced by infants whose mothers are working full-time constitute a "risk" factor for the development of "insecure-avoidant" infant-mother attachments.

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Two samples of insulin-dependent diabetic youths were studies in successive attempts to refine a brief patient self-report measure of general long-term adherence to a diabetic regimen. Validity and reliability were assessed for both samples by measuring a number of related variables: locus of control, stressful life events, knowledge of diabetes, parent report, and glycosylated hemoglobin. Initial evidence of validity was demonstrated in a variety of criterion areas. Both reliability and validity were replicated on the second sample. Adherence is discussed as a complex multidimensional variable, the measurement of which requires several different methods, including the selfreport measure described here. Warnings about social desirability as a confounding factor were discussed, as were suggestions for other adherence measures.

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The authors tested the relationship between psychosocial childbearing stress factors and metabolic control in a research sample of 39 pregnant insulin-dependent diabetic women. Subjects were selected using rigorous exclusion criteria from a population of more than 200 pregnant diabetic patients assessed in a University National Institutes of Health Center. Metabolic control was determined by plasma levels of preprandial day, night, and early morning fasting glucose, urinary ketones, and glycosylation of hemoglobin. Differences in plasma glucose concentrations and urinary ketone levels at several times during the day and night were associated with psychosocial stress factors. A similar relationship between stress and levels of diabetic control could not be demonstrated by hemoglobin A1 assay, a result contradicting most prior studies of adolescent populations. These findings are compatible with a biopsychosocial model of diabetes mellitus and emphasize the importance of using several different measures of diabetic control to determine stress-control relationships.

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Psychosomatic research findings correlating psychologic stress with diabetic control fail as yet to provide valid conclusions. Investigators have presented many contradictory findings. The two major pathways by which stress could affect control, a) changes in compliance behavior, and b) a neurohumoral axis, have not been clearly distinguished from each other. The study of adolescent cohorts is associated with the problem of heterogeneity, limiting the application of results to other diabetic populations. Methods of determining diabetic control have been incomplete and the definition and measurement of stress have major inadequacies for the analysis of such a complex psychosomatic problem. Existing evidence is comprehensively reviewed and evaluated. The authors use a modified definition of stress to construct a stress scale specific to pregnant diabetics.

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Forty-two insulin-dependent latency and adolescent age diabetics were studied over a four-month period. Half of the population received a multicomponent intervention designed to enhance diabetic regulation. Psychological and demographic variables and glycosylation of hemoglobin were correlated in order to investigate the interaction between personality factors and metabolic control. Number of life event changes predicted initial values of glycohemoglobin, while ego development predicted the magnitude of improved diabetic control.

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One hundred pregnant diabetic patients have been prospectively studied in the first large-scale systematic evaluation of emotional behavior and psychosocial factors influencing psychiatric behavior in the pregnant diabetic patient. A Psychiatric Risk Scale including ten weighted medical and psychosocial factors has been developed to identify patients at high risk for psychiatric illness or poor compliance. This scale significantly increases the data base of classic "neglector" characteristics described by Pederson in 1965. Early identification of psychiatrically high-risk patients in concert with brief relevant psychodynamic exploration offers the potential of more directed care to a subset of patients at increased risk for poor perinatal performance.

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Morbidity risks continue to constitute a major problem for the premature infant, despite striking progress in neonatal care and technology. This article reviews the early stimulation literature over the past 15 years, and discusses the findings of improved weight gain, respiratory status and psychomotor development when infants are stimulated early in life. Although some authors have criticized this area of research because of methodological problems, the overwhelming evidence points to the beneficial consequences of tactile and vestibular stimulation programs in high-risk nurseries. Further research is, however, clearly indicated in order to more fully elucidate the major variables and mechanisms responsible for the experimental effects, and to elaborate a more standardized program of psychological care of premature infants.

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In a large company, a group of problem drinker employees selected from the Alcoholic Rehabilitation Program at Illinois Bell, and a group of supervisors of such employees were participants in the study. Questionnaires as well as interviews were utilized. Comparative tables were discussed. A definite, yet flexible role of the supervisor was seen operative throughout the different processes of recognition, confrontation, referral, and treatment. Certain conclusions were drawn from the perspective of the patients, the supervisors, and the company.

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