RESUMEN
BACKGROUND: In the recent years, the ever increasing tendency toward the growth in the prevalence of degenerative-dystrophic articular diseases has been observed especially among the young subjects and the middle-aged people. The enhanced economic burden of treating the patients with this condition on the public health care system frequently comes not only from chronic pathology of the joints but also from the development of concomitant disorders which dictates the necessity of the search for the new methods for the management of such patients. AIM: The objective of the present study was the optimization of the treatment of the patients presenting with stage I-II gonarthrosis by the para-articular application of oxygen/ozone therapy at the early stages of knee arthritis and the evaluation of the clinical effectiveness of this approach. MATERIAL AND METHODS: A total of 89 patients suffering from I-II sg gonarthrosis were recruited for the participation in the study. They included 67.2% of men and 32.8% of women. The age of the patients varied from 33 to 54 (mean 42±5) years, the duration of the disease averaged 4±1.2 years. All the patients were randomly divided into two groups: matched for the age, gender, the duration and severity of the disease, and the methods of its treatment. The main group was comprised of 45 patients whereas the group of comparison consisted of 44 patients. The generally accepted therapeutic modalities were used to treat the patients of both groups. Those included in the main group (n=45) additionally received para-articular oxygen/ozone therapy applied to the affected knee at a permanent ozone concentration of 8 gr/l (the injection area 15-20 sq.cm), main group n=45). The results of the treatment were evaluated within 1 and 6 months after the onset of therapy. RESULTS: The application of the up-to-date methods of oxygen/ozone therapy in the combination with the universally-accepted drug-based treatments for the patients of the main group resulted in the significant (p<0.01) improvement of the indicators of the biomechanical activity of the knee joints in comparison with that achieved by means of the generic drug-based treatment alone. DISCUSSION: The results of the present study give evidence of the feasibility of application of oxygen/ozone therapy for the treatment of degenerative-dystrophic articular diseases of the knees. The positive dynamics of the indicators of the functional activity of the knee joints, intensity and duration of the pain syndrome as well as the reduction of the period of the temporary incapacity for work associated with exacerbation of knee arthrosis suggests the high clinical and economic effectiveness of the para-articular application of oxygen/ozone therapy. CONCLUSIONS: The present study has demonstrated the expediency and effectiveness of the application of oxygen/ozone therapy during exacerbation of stage Ð-ÐÐ knee arthritis as evaluated based on the WOMAC index, VAS, and Lyshom scale within one and six months after the onset of the treatment. The resulting reduction in the number of days of temporary incapacity for work in the patients suffering from knee arthritis gives evidence of the clinical and economic validity of the proposed method of the combined treatment of this condition based on the application of oxygen/ozone therapy.
Asunto(s)
Osteoartritis de la Rodilla/rehabilitación , Oxígeno/uso terapéutico , Ozono/uso terapéutico , Adulto , Femenino , Humanos , Articulación de la Rodilla/fisiología , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/fisiopatología , Resultado del TratamientoRESUMEN
An examination of 150 patients suffering from pathological gambling (PG) has shown that a PG predisposition includes 3 components: personal, morphofunctional and gender. The personal component is a combination of lability and hyperthymia, higher extraversion, easy communication, riskiness, low empathic ability, inclination to emotional satiation. The morphofunctional component embraces structural (a pathology of cortical and subcortical areas, localized mainly in the frontal region and limbic structure of brain) and functional (abnormalities of regulatory processes, signs of cerebral immaturity) peculiarities of the central nervous system. The gender component is reflected in the notable predominance of males, weak and medium-weak sexual constitution, psychosexual development peculiarities manifested as a reduced romantic stage. This complex predisposition, though non-fatal, raises the risk of the disorder.
Asunto(s)
Conducta Adictiva/etiología , Trastornos Disruptivos, del Control de Impulso y de la Conducta/etiología , Juego de Azar/psicología , Adolescente , Adulto , Conducta Adictiva/diagnóstico , Conducta Adictiva/epidemiología , Diagnóstico Diferencial , Progresión de la Enfermedad , Trastornos Disruptivos, del Control de Impulso y de la Conducta/diagnóstico , Trastornos Disruptivos, del Control de Impulso y de la Conducta/epidemiología , Femenino , Humanos , Incidencia , Masculino , Psicometría , Factores de Riesgo , Federación de Rusia/epidemiología , Adulto JovenRESUMEN
The principal idea of the method of surgery is the division of patients into two groups: a group of patients with a stable process and a group of patients with the disease in the stage of non-cupped exacerbation. When using any surgical interventions one should follow the principle of maximum preservation of the functioning lung tissue, the surgery being performed in the size of destructive changes in the lungs. In a unilateral cavernous injury resection of the lung or pneumonectomy was the main method of surgery. In the treatment of patients with bilateral caverns the main line of the surgical tactics is the planned bilateral surgical treatment, individual selection of the optimal combination of different operations, division of the surgical treatment into steps and choice of their sequence.