RESUMEN

Among sites of extrapulmonary growth of Mycobacterium tuberculosis, the liver is the least infected. Our data suggest that this is due to the complete restriction of mycobacterial growth to liver macrophages. Unlike in organs more persistently seeded by M. tuberculosis, in the liver the bacteria do not infect cell types other than professional phagocytes.

Asunto(s)

Hígado/microbiología , Macrófagos/microbiología , Mycobacterium tuberculosis/patogenicidad , Tuberculosis/microbiología , Animales , Recuento de Colonia Microbiana , Hígado/citología , Pulmón/microbiología , Ratones , Ratones Endogámicos C57BL , Bazo/microbiología