RESUMEN
The authors review the published data on antibodies to endothelial cells observed in patients suffering from diffuse connective tissue diseases. In these patients the histologic lesions are found in vessels of different sizes and localizations. It is believed that such auto-antibodies may have a role in the pathogenesis and prognosis of these disorders. The preliminary results of a study of the antigenicity of endothelial cells in mixed connective tissue disease are also presented.
Asunto(s)
Autoanticuerpos/análisis , Enfermedades del Tejido Conjuntivo/inmunología , Endotelio Vascular/inmunología , Autoanticuerpos/inmunología , HumanosRESUMEN
Soft tissue rheumatism or "non-articular rheumatism" represents a group of diverse entities, the common feature of which is muscular stiffness and pain. It is the major cause of morbidity and loss of productive man-hours at work. There is no internationally accepted classification of the soft tissue rheumatism. On hand of an arbitrary classification of the soft tissue rheumatism the affections are divided in localized, regional and generalized conditions.
Asunto(s)
Polimialgia Reumática , Humanos , Enfermedades Musculares/etiología , Enfermedades Musculares/fisiopatología , Polimialgia Reumática/etiología , Polimialgia Reumática/fisiopatologíaRESUMEN
The authors review the conventional methods for the management of the soft tissue rheumatism. The success in relieving the patient's chief complaint, i.e. pain, depends on the choice of the appropriate measures that can be used without inconvenience to the patients.
Asunto(s)
Polimialgia Reumática/terapia , HumanosRESUMEN
Attention is called to mixed connective tissue disease which, twenty years after it's original description, has now reached the syndromic individualization with important therapeutic and prognostic implications. In particular the discussion concerns the pulmonary complications (hypertension and fibrosis) responsible frequently for fatal outcome.