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1.
Med Pharm Rep ; 96(1): 79-85, 2023 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-36818323

RESUMEN

Aim: To evaluate the cleaning ability of two single-file rotary systems- Self-Adjusting File (SAF) and Wave one (WO) systems in removing the smear layer using sodium hypochlorite (NaOCl) + ethylene diamine tetraacetic acid (EDTA) and NaOCl + Qmix as irrigants at apical one-third of the root canal. Methods: Forty extracted human mandibular premolars were selected and working length was determined. The canal was manually instrumented up to a number 25 size K-file. The roots were divided into the following groups with 10 samples each - Group 1 using SAF: Group 1a- 3% NaOCl + 17% EDTA, Group 1b- 3% NaOCl + Qmix. Group2 using WO: Group 2a- 3% NaOCl + 17% EDTA, Group 2b- 3% NaOCl + Qmix. In the SAF group, the irrigation was performed continuously using the special irrigation apparatus. In the WO group, syringe irrigation was done followed by final irrigant activation using passive ultrasonic irrigation (PUI). The roots were sectioned longitudinally and subjected to scanning electron microscopic (SEM) examination. The amount of smear layer was evaluated using a five score index at the apical third level. Statistical analysis was performed using the Chi-square test. Results: Group 1 (SAF) showed better canal cleanliness at apical third compared to Group 2 (WO) with both irrigant combinations and the results were statistically significant (p<0.05). 3% NaOCl + Qmix was equally as effective as 3% NaOCl + 17% EDTA in removing the smear layer with no significant difference between them. Conclusion: Within the limitation of this study, SAF in combination with 3% NaOCl + Qmix or 3% NaOCl + 17% EDTA should be used for removing smear layer in critical areas of the root canal.

2.
J Contemp Dent Pract ; 23(12): 1211-1217, 2022 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-37125518

RESUMEN

AIM: This randomized controlled trial evaluated the efficacy of platelet-rich fibrin (PRF) and concentrated growth factor (CGF) as scaffolds in the regenerative endodontic procedure (REP) using clinical and radiographic parameters along with cone-beam computed tomographic (CBCT) analysis. MATERIALS AND METHODS: The apexogenesis procedure was performed in 16 teeth. They were randomly divided into two groups of eight teeth each: group I and group II. In group I PRF was used as the scaffold and in group II CGF was used as the scaffold. They were evaluated for pain, pulpal vitality, tenderness on percussion, and mobility, and also evaluated using digital radiographs at 3, 6, 12, and 18 months interval. The response of the teeth was graded using Chen and Chen criteria. Increase in root length, reduction in the apical foramen dimension, and reduction in periapical lesion volume were evaluated using CBCT scans taken preoperatively and at 18 months. RESULTS: At the end of 3 months, 50% of teeth without periapical pathology were found to be vital in both groups. At the end of 18 months, 60% of the teeth in both groups showed increase in root length, all teeth showed closure of apical foramen, and reduction in the volume of periapical lesion. However, there was no statistically significant difference between the groups (p < 0.05). CONCLUSION: The clinical and radiographic features reported in this study revealed that both PRF and CGF act as effective scaffolds in REP for regeneration of pulp-dentin complex with promising results. CLINICAL SIGNIFICANCE: Apexogenesis by revascularization has not been used regularly for the treatment of nonvital teeth with open apex because the results are not reliable. Since platelet concentrates like PRF and CGF are rich in growth factors; when apexogenesis is performed by REP using these platelet concentrates, desirable results can be achieved in a short duration of time. They also accelerate the healing of periapical lesions present in such cases. With the increased success rate of apexogenesis with REP, many clinicians would prefer to use REPs as a treatment option for teeth with open apex.


Asunto(s)
Fibrina Rica en Plaquetas , Endodoncia Regenerativa , Humanos , Pulpa Dental , Necrosis de la Pulpa Dental , Péptidos y Proteínas de Señalización Intercelular/uso terapéutico
3.
Contemp Clin Dent ; 10(3): 542-547, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-32308334

RESUMEN

AIM: This study aims to compare the cleaning efficacy of root canal walls using two rotary single file systems: self-adjusting file (SAF) and WaveOne (WO). MATERIALS AND METHODS: Forty extracted human premolars with similar range of canal curvature were selected, decoronated, working length determined and roots were divided into two groups of 20 samples each: Group I - SAF and Group II - WO. All root canals were irrigated with 3% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA). The roots were sectioned longitudinally and subjected to scanning electron microscopic examination. The amount of debris and smear layer was evaluated using five score index at coronal, middle and apical third levels. Statistical analysis was performed using the Chi-square test and significance was set at a P < 0.05. RESULTS: Statistically significant difference was observed between the groups in cleaning the apical third. Group I (SAF) showed better canal cleanliness compared to Group II (WO) in the apical third. CONCLUSION: Within the limitations of this study, SAF in combination with 3% NaOCl and 17% EDTA irrigating solution had significantly better cleaning efficacy in the apical third of root canals when compared to WO rotary file system.

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