RESUMEN

Standardized complex of low-molecular peptides from the heart, cordialin, stimulates functional activity of cardiomyocytes and mobilizes their protective mechanisms against the effect of the industrial and agricultural poison tetramethylthiuram disulfide (TMTD). The cardioprotective effect of cordialin is most marked in the restoration period when it was administered after TMTD damage to the cardiomyocytes.

Asunto(s)

Cardiomiopatías/tratamiento farmacológico , Fármacos Cardiovasculares/farmacología , Péptidos/farmacología , Tiram/antagonistas & inhibidores , Animales , Cardiomiopatías/inducido químicamente , Femenino , Péptidos y Proteínas de Señalización Intercelular , Masculino , Ratas