RESUMEN
Trichinellosis is an emerging or re-emerging foodborne parasitic zoonotic disease caused by nematodes of the genus Trichinella. It represents a global food safety problem and a public health hazard. This case report aims to describe the first case of human trichinellosis in Portugal since the creation of the European Union surveillance system. Infection by Trichinella spp. is a rare cause of hypereosinophilia and hospital admission, but it can cause high morbidity. Clinical detailed history is crucial to obtain a correct diagnosis.
RESUMEN
We describe a 7-year-old boy with dermatitis herpetiformis (DH) diagnosed on clinical and histologic evidence, negative direct immunofluorescence (DIF) findings for junctional IgA deposits in uninvolved skin, positive IgA endomysial and gliadin antibodies, and jejunal biopsy revealing a gluten-sensitive enteropathy. Treatment with dapsone led to the disappearance of cutaneous lesions and pruritus within 48 hours. Demonstration of IgA immune deposits in the dermal papillae has been the only acceptable criterion for the diagnosis of dermatitis herpetiformis. However, considering several reports in the literature of DH with a negative DIF and our own case, we believe that in the absence of the characteristic DIF pattern, one needs the combination of clinical, histologic, and immunologic data to support the diagnosis of DH. We also discuss recent developments in the diagnosis of DH.
Asunto(s)
Dermatitis Herpetiforme/diagnóstico , Técnica del Anticuerpo Fluorescente Directa/métodos , Biopsia con Aguja , Niño , Dapsona/administración & dosificación , Dermatitis Herpetiforme/tratamiento farmacológico , Dermatitis Herpetiforme/patología , Estudios de Seguimiento , Humanos , Inmunohistoquímica , Masculino , Sensibilidad y Especificidad , Índice de Severidad de la Enfermedad , Resultado del TratamientoRESUMEN
Descrevemos o caso clínico de um doente com papulose bowenóide localizada na pele da prega inguino-escrotal direita, tendo sido feita comprovaçao histopatológica e identificaçao de Papilomavírus Humano tipo 16 em material de biópsia.