RESUMEN
The activity of the kallikrein-kinin, prostaglandin and cyclase systems was assessed in 117 patients with chronic pyelonephritis with and without arterial hypertension. Pyelonephritis is shown to be associated with a dysfunction of the pressor-depressor mechanisms examined, featuring a depression of vasodepressor reactions. Patients with normal, increased and depressed humoral parameters could be found in each study group, the changes being particularly marked in patients with chronic pyelonephritis, combined with arterial hypertension.
Asunto(s)
Calicreínas/orina , Riñón/fisiopatología , Cininas/orina , Prostaglandinas/orina , Pielonefritis/orina , Adolescente , Adulto , Anciano , Enfermedad Crónica , Femenino , Humanos , Hipertensión/fisiopatología , Hipertensión/orina , Masculino , Persona de Mediana Edad , Pielonefritis/fisiopatologíaRESUMEN
Comparative study of the renal and blood kinin system in patients with hypertensive disease and in those with chronic pyelonephritis revealed its different reaction to a similar character of arterial pressure in these patients, which suggests that the kinin system differs in its significance in the pathogenesis of hypertension in these diseases. It is recommended to use the values of the renal and blood kinin system in practice for the differential-diagnostic purpose in the planned stage-by-stage examination of patients with arterial hypertension.