RESUMEN
The study in Algeria over a period of 3 years of 90 cases of idiopathic thrombopenic purpura out of 409 hemorrhagic syndromes, showed the following peculiarities: the chronic forms are as frequent in the child as in the adult and we did not observe any subacute forms. Except in one case the use of prednisone at a dose of 2 mg/kg gave no result in patients who were not improved by a dose of 1 mg/kg.
Asunto(s)
Púrpura Trombocitopénica/epidemiología , Adolescente , Adulto , Anciano , Argelia , Niño , Enfermedad Crónica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Prednisona/uso terapéutico , Púrpura Trombocitopénica/tratamiento farmacológicoRESUMEN
The clinical, hematological and therapeutic aspects of 36 cases of acute myeloblastic leukemia in children and 98 cases in adults observed in Algeria are discussed. In Algeria, acute myeloblastic leukemia is more frequent in children than in other populations. In our series there was a very unusual female predominance. Clinically, we observed in children only, 8 cases of chloroma of the orbit. From the hematological point of view, the only difference was a higher incidence of leukopenia and hyperleukocytosis after the age 30 years. The results of VAMP treatment (vincristin, amethopterin, 6-mercaptopurine, and prednisone) are better in children than in adults. But analysis of the results is more interesting if one places the patients in age groups of ten years. The percentage of complete remissions is maximum in the age group 0 to 10years and then falls regularly.