RESUMEN

The authors evaluated the efficacy and tolerance of low dose lymphoblastoid alpha interferon in 14 i.v. drug addicts with histologically confirmed chronic active hepatitis C. Patients were treated for 12 months; all completed the whole treatment without complaining of significant side effects. Four months after withdrawal of treatment, 13 patients were found to be in clinical and biohumoral remission with serum transaminases within the normal range already after 12 weeks.

Asunto(s)

Seronegatividad para VIH , Hepatitis C/terapia , Hepatitis Crónica/terapia , Interferón-alfa/uso terapéutico , Abuso de Sustancias por Vía Intravenosa/complicaciones , Adulto , Ensayo de Inmunoadsorción Enzimática , Femenino , Hepacivirus/inmunología , Anticuerpos Antihepatitis/análisis , Hepatitis C/diagnóstico , Anticuerpos contra la Hepatitis C , Hepatitis Crónica/diagnóstico , Humanos , Immunoblotting , Interferón-alfa/administración & dosificación , Interferón-alfa/efectos adversos , Interferones , Masculino , Factores de Tiempo