RESUMEN

Application of multivariate curve resolution alternating least squares (MCR-ALS), for the resolution and quantification of different analytes in different type of pharmaceutical and agricultural samples is shown. In particular, MCR-ALS is applied first to the UV spectrophotometric quantitative analysis of mixtures of commercial steroid drugs, and second to the near-infrared (NIR) spectrophotometric quantitative analysis of humidity and protein contents in forage cereal samples. Quantitative results obtained by MCR-ALS are compared to those obtained using the well established partial least squares regression (PLSR) multivariate calibration method.

Asunto(s)

Productos Agrícolas/química , Preparaciones Farmacéuticas/análisis , Espectrofotometría Ultravioleta/métodos , Espectroscopía Infrarroja por Transformada de Fourier/métodos , Grano Comestible/química , Procesamiento Automatizado de Datos/métodos , Análisis de los Mínimos Cuadrados , Análisis Multivariante , Preparaciones Farmacéuticas/química , Proteínas/análisis , Espectrofotometría Ultravioleta/estadística & datos numéricos , Espectroscopía Infrarroja por Transformada de Fourier/estadística & datos numéricos , Esteroides/análisis