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2.
Crit Care Med ; 16(1): 27-33, 1988 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-3338278

RESUMEN

Meningococcal shock still is associated with high mortality. Along with antibiotics and control of metabolic derangements, standard therapy involves monitoring and maintaining numerous cardiorespiratory variables. From 1980 to 1985, 39 children with meningococcal shock were treated in our pediatric ICU. We obtained full hemodynamic monitoring in 18 (12 survivors, six nonsurvivors). Two hemodynamic patterns were observed: hypovolemia and cardiac failure. Early death was generally related to refractory hypovolemia, probably secondary to severe capillary leak. Survival usually occurred when noticeable cardiac failure was controlled with early use of catecholamines and judicious fluid management. Because cardiac failure only slowly recovered, a therapeutic approach that aims not at normal variables but, rather, at survival variables seems appropriate.


Asunto(s)
Hemodinámica , Infecciones Meningocócicas/fisiopatología , Choque Séptico/fisiopatología , Volumen Sanguíneo , Gasto Cardíaco , Niño , Preescolar , Femenino , Insuficiencia Cardíaca/etiología , Frecuencia Cardíaca , Humanos , Lactante , Unidades de Cuidados Intensivos , Masculino , Infecciones Meningocócicas/mortalidad , Infecciones Meningocócicas/terapia , Presión Esfenoidal Pulmonar , Choque Séptico/mortalidad , Choque Séptico/terapia
3.
Intensive Care Med ; 13(1): 65-70, 1987.
Artículo en Inglés | MEDLINE | ID: mdl-3558938

RESUMEN

There are no reports analyzing the results of pediatric intensive care in Europe. We evaluated quantitatively the severity of illness and the amount of care required for 714 consecutively admitted patients. We used simultaneously the Clinical Classification System (CCS) the Acute Physiology Score (APS) and the Therapeutic Intervention Scoring System (TISS). Overall mortality at 1 month was 15%. The mortality rate was higher for CCS Class IV patients (32.3%) than for CCS III (4.5%) and CCS II (3.2%). The difference was significant between CCS IV and CCS III and II respectively (p less than 0.001) but no difference was observed between CCS III and CCS II. The patients were also classified among 7 major organ system failures: cardio vascular, respiratory, neurologic, gastro intestinal, renal, metabolic, hematologic. Three of them were primarily involved: respiratory (44.9%) cardio-vascular (20.7%), neurologic (18.8%). Among these 3 groups the highest mortality was observed in cardio-vascular patients (p less than 0.01 v.s. respiratory, p less than 0.05 v.s. neurologic). The death rate was 22% among the 264 neonates, 9.7% among the 247 infants (p less than 0.01) and 12.6% among the 198 children. APS and TISS scores increased significantly with the CCS classes.(ABSTRACT TRUNCATED AT 250 WORDS)


Asunto(s)
Unidades de Cuidados Intensivos/normas , Niño , Preescolar , Europa (Continente) , Femenino , Humanos , Lactante , Recién Nacido , Unidades de Cuidados Intensivos/estadística & datos numéricos , Tiempo de Internación , Masculino , Mortalidad , Evaluación de Procesos y Resultados en Atención de Salud , Índice de Severidad de la Enfermedad
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