RESUMEN
A rich body of work has reported levels of infection with Toxocara species in definitive hosts, and the frequency of eggs in the environment, in many different regions and situations. These have greatly increased our understanding of the relationship between egg excretion from companion and wild animals and the risk of human infection by inadvertent ingestion of eggs from soil and other environmental reservoirs. Nevertheless, it is difficult to compare studies directly because of vagaries in sampling and laboratory methods, a preponderance of prevalence rather than abundance data, and a lack of studies that systematically sample different sympatric definitive host populations. Such comparisons could be instructive, for example to determine the relative contributions of different definitive host populations and categories to environmental contamination in specified areas, and hence guide priorities for control. In this article we use estimates of host density and infection levels in the city of Bristol, UK, as a case study to evaluate the relative contribution of sympatric cats, dogs and foxes to overall environmental contamination with eggs. Results suggest that dogs, especially those less than 12 weeks of age, dominate total egg output, but that this is modified by degree of access to public areas and removal of faeces, such that foxes could take over as the primary source of eggs. Results and conclusions are likely to differ among specific locations. The general aim is to show how an improved quantitative framework for epidemiological studies of Toxocara spp. egg contamination can help to advance understanding and the effectiveness of control strategies in future.
Asunto(s)
Enfermedades de los Gatos/epidemiología , Enfermedades de los Perros/epidemiología , Zorros/parasitología , Suelo/parasitología , Toxocara/aislamiento & purificación , Toxocariasis/epidemiología , Animales , Enfermedades de los Gatos/parasitología , Gatos , Enfermedades de los Perros/parasitología , Perros , Heces/parasitología , Femenino , Humanos , Modelos Biológicos , Óvulo , Recuento de Huevos de Parásitos/veterinaria , Densidad de Población , Prevalencia , Salud Rural , Sensibilidad y Especificidad , Toxocara canis/aislamiento & purificación , Toxocariasis/parasitología , Reino Unido/epidemiología , Salud UrbanaRESUMEN
The effects of concentration (1, 10, 100 microg/L) and duration (4, 8, 12 h) of exposure to carbofuran were assessed on the swimming activity, social interactions, and behavioral responses of goldfish to a flow (0.1 L/min) of water, with or without chironomids. Observations were also made on the behavioral responses of unexposed goldfish to a flow (0.1 L/min) of carbofuran-contaminated water. A 4-h exposure of goldfish 1 microg/L carbofuran produced a significant increase in sheltering, burst swimming, and nipping. Responses were enhanced at 100 microg/L. After a 12-h exposure, the behavioral effects of 1 microg/L carbofuran were less apparent. However, burst swimming at 10 microg/L, and sheltering, nipping and burst swimming at 100 microg/L, were still significantly increased after a 12-h exposure to carbofuran. Grouping was not consistently affected by exposure conditions. Chemical attraction to a filtrate of chironomids was significantly reduced after the 4-h exposure to 1 microg/L carbofuran. Decreased attraction to the food extract was less apparent after the 12-h exposure, except at 100 microg/L carbofuran. A significant decrease in attraction to a flow of uncontaminated water was also observed after a 4-h exposure to 10 and 100 microg/L carbofuran. Unexposed goldfish did not show avoidance reaction to a flow of carbofuran-contaminated water, even at a concentration (10 mg/L) exceeding the mean 96-h LC-50 in cyprinids (0.5-1 mg/L). However, at all concentrations tested (0.1, 1, 10 mg/L), goldfish quickly reacted to the introduction of the solution of carbofuran by increased burst swimming and nipping. These results are discussed in the light of the data concerning behavioral and neurotoxic effects of carbamate and organophosphorous insecticides in fish.