RESUMEN

PURPOSE OF REVIEW: Few procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies. RECENT FINDINGS: Mannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR). We review the current evidence for the use of mannitol and its effects on these procedures.

Asunto(s)

Diuréticos Osmóticos/uso terapéutico , Trasplante de Riñón/métodos , Manitol/uso terapéutico , Nefrectomía/métodos , Daño por Reperfusión/prevención & control , Tasa de Filtración Glomerular , Humanos , Riñón/irrigación sanguínea , Daño por Reperfusión/etiología , Isquemia Tibia/efectos adversos