RESUMEN
The aquatic ecosystem is constantly being disturbed by rising levels of different classes of pollutants of human origin in the form of urban, agricultural and industrial discharges. In this study, the health of fish Malapterurus electricus was examined, to serve as a reflection of the impact of anthropogenic disturbances in the Lekki lagoon. Eighty six samples of the fish were analysed for parasitic infections, heavy metals, microorganisms in their internal and external body parts while the proximate composition and fish condition factor were also determined using conventional methods. One parasite species, a cestode Electrotaenia malapteruri was found to infect the fish. Total parasite load was eighty five with a total prevalence of infection of 36%. Elements detected in sediment were of the order of Al>Fe>Mn>Pb>Cr>Zn>Cd>Ba>Cu>Ni while in water, it is Mn>Fe>Zn>Ba>Cd>Cr>Al>Cu>Ni>Pb. Metals analysed in the fish tissues were generally low and below regulatory limits. In the proximate analysis, moisture content has a value of 80.7%, while ash content had a value of 1.26%. Eight bacterial and two fungal species were isolated from the fish. The condition factor of fish varied between 1 and 2. The study provides valuable information for monitoring and management of heavy metal pollution in the aquatic ecosystem.
RESUMEN
Heavy metal toxicity in aquatic life as a result of human activities poses a grave health threat to water quality, aquatic and human life. Parasites may serve as indicators of heavy metal pollution. This research investigated the health status of the fish Heterotis niloticus viz-a-viz quality of the water and sediments in Lekki lagoon, parasitic infection, presence of heavy metals and oxidative stress response in the liver and intestine of the fish. Parasites recovered were also analyzed for the extent of bioaccumulation of heavy metals. The metals in water, sediments, parasites, and fish were analyzed using Atomic Absorption Spectrometry. Heavy metal concentrations in the surface water were generally below regulatory limits of World Health Organization. Sediment had high levels of aluminium (124.78 mg/kg) and iron (327.41 mg/kg); other heavy metals were below regulatory limits. Tenuisentis niloticus, an acanthocephalan, was the only parasite recovered. Seventy (70) out of 100 fish sampled were infected with the parasite. T. niloticus bioaccumulated Cd, Ni, and Pb between 65 to 100 times more than the liver and 12 to 200 times more than the intestine. Other metals bioaccumulated from the host tissues by the parasite had the magnitude between 1 to 12 times as the liver and 1 to 30 times as the intestine. There were significant differences in the activities of antioxidant enzymes between the parasitized and non-parasitized fishes. Fish tissues also showed histological alterations, ranging from mild infiltration of inflammatory cells to moderate inflammation and haemorrhagic lesions. Human activities that introduce stressors into the lagoon should be controlled.
RESUMEN
Toxicity studies in the aquatic ecosystem have shown that petrol and its product have adverse effects on aquatic biota. They are able to easily absorb these toxic substances into their bodies from sediment, water or even food items that are contaminated, thus impacting the food chain. In this study, water, sediment and fish (Heterotis niloticus) from the Epe Lagoon were investigated for the presence of BTEX (benzene, toluene, ethylbenzene and the three xylene isomers m, o and p-xylenes), and PAHs using GC-MS. Total concentration of BTEX in sediment and water was respectively 32.37 ± 1.07 µg/g, 49.86 ± 7.30 µg/L; while total concentration of BTEX in fish liver and intestine was 33.75 ± 10.09 and 40.16 ± 9.64 µg/g respectively. Benzene, 1,2-Dichlorobenzene and 1,3-Dichlorobenzene components of BTEX were not detected in both sediment and water. Total concentration of PAH in sediment and water was 7.46 ± 1.73 µg/g and 19.33 ± 1.31 µg/L respectively. Total PAHs concentration in liver and fish intestine was 141.23 ± 5.89 and 173.34 ± 4.677 µg/g respectively. Majority of the PAHs congeners were found to be higher than the acceptable limits. Findings from this study shows the need for continuous monitoring of our natural waters as the present situation portends a potential concern for ecological risk.
RESUMEN
The aquatic environment is continuously at the mercy of man's negative impact on it. This study was designed to determine the proximate composition and concentration of some heavy metals in four fish species - Oreochromis niloticus, Malapterurus electricus, Parachanna obscura, Chrysichthys nigrodigitatus in Ogun River, Nigeria. The fish species were collected from the Abeokuta axis of the river and analyzed for Manganese (Mn), Lead (Pb), Nickel (Ni), Cadmium (Cd) and Zinc (Zn) using atomic absorption spectrometry. The moisture, crude protein, ash and fat content of the four fish species were analyzed using standard methods. The results showed varying levels of accumulation of the metals among the four fish species. Pb was detected only in Oreochromis niloticus while Mn was detected only in Chrysichthys nigrodigitatus. Except in a few cases, Pb and Ni in muscles of Oreochromis niloticus and Parachanna obscura respectively, the liver and gills accumulated more metals than the muscles. The concentrations of the metals in all cases were beyond regulatory limits by International Standards. All the fishes had high moisture content between 75 and 80 %, while fat was the lowest nutrient (0.88-1.89 %) in all fish species. The differences in proximate values were not significant among fish species. The findings in this study may be a reflection of the pollution status of the Ogun River with heavy metals while also portraying the risk associated with the consumption of fish from the river.
RESUMEN
BACKGROUND: The resistance of human malaria parasites to anti-malarial compounds has become considerable concern, particularly in view of the shortage of novel classes of anti-malarial drugs. One way to prevent resistance is by using new compounds that are not based on existing synthetic antimicrobial agents. RESULTS: Sensitivity of 100 Plasmodium falciparum isolates to chloroquine, quinine, amodiaquine, mefloquine, sulphadoxine/pyrimethamine, artemisinin, Momordica charantia ('Ejirin') Diospyros monbuttensis ('Egun eja') and Morinda lucida ('Oruwo') was determined using the in vitro microtest (Mark III) technique to determine the IC50 of the drugs. All the isolates tested were sensitive to quinine, mefloquine and artesunate. Fifty-one percent of the isolates were resistant to chloroquine, 13% to amodiaquine and 5% to sulphadoxine/pyrimethamine. Highest resistance to chloroquine (68.9%) was recorded among isolates from Yewa zone while highest resistance to amodiaquine (30%) was observed in Ijebu zone. Highest resistance to sulphadoxine/pyrimethamine was recorded in Yewa and Egba zones, respectively. A positive correlation was observed between the responses to artemisinin and mefloquine (P<0.05), artemisinin and quinine (P<0.05) and quinine and mefloquine (P<0.05). A negative correlation was observed between the responses to chloroquine and mefloquine (P>0.05). Highest anti-plasmodial activity was obtained with the ethanolic extract of D. monbuttensis (IC50 = 3.2 nM) while the lowest was obtained from M. lucida (IC50 = 25 nM). CONCLUSIONS: Natural products isolated from plants used in traditional medicine, which have potent anti-plasmodial action in vitro, represent potential sources of new anti-malarial drugs.