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1.
Ginecol Obstet Mex ; 68: 429-34, 2000 Oct.
Artículo en Español | MEDLINE | ID: mdl-11138405

RESUMEN

We report two cases of vulvar sarcomas that are our Institutional experience in 29 years. The first case was a teenager of 14 years-old with a low grade leiomyosarcoma surgically treated. Along a 22 years follow-up the disease has had four local recurrences of more than 5 cm each one: two after surgery and two after surgery plus chemotherapy and surgery plus radiotherapy respectively. She is alive disease evidence after two years from the last combined treatment. The second one, was a 26 years-old patient with a malignant schwannoma of 12 cm in diameter treated with combined radical surgery, radiotherapy, and chemotherapy. She is alive and without disease evidence 52 months after surgery. We emphasized that these tumors are very rare and the fact that the first patient is the youngest and with more years of follow up according the bibliography consulted. Treatment of vulvar sarcomas is radical local excision followed mainly by radiotherapy with infiltrating margins. The value of postoperative adjuvant chemotherapy is uncertain. According to the natural history and behavior of vulvar sarcomas, we conclude that the elective treatment of these tumors should be carry out in institutions of high level.


Asunto(s)
Leiomiosarcoma , Neurilemoma , Neoplasias de la Vulva , Neoplasias Abdominales/tratamiento farmacológico , Neoplasias Abdominales/radioterapia , Neoplasias Abdominales/secundario , Adolescente , Adulto , Antineoplásicos Alquilantes/uso terapéutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Glándulas Vestibulares Mayores , Quimioterapia Adyuvante , Terapia Combinada , Ciclofosfamida/administración & dosificación , Cistectomía , Quistes/diagnóstico , Dacarbazina/administración & dosificación , Dacarbazina/uso terapéutico , Diagnóstico Diferencial , Supervivencia sin Enfermedad , Doxorrubicina/administración & dosificación , Femenino , Estudios de Seguimiento , Humanos , Leiomiosarcoma/diagnóstico , Leiomiosarcoma/tratamiento farmacológico , Leiomiosarcoma/radioterapia , Leiomiosarcoma/secundario , Leiomiosarcoma/cirugía , Recurrencia Local de Neoplasia , Neurilemoma/tratamiento farmacológico , Neurilemoma/radioterapia , Neurilemoma/cirugía , Neoplasias Pélvicas/tratamiento farmacológico , Neoplasias Pélvicas/radioterapia , Neoplasias Pélvicas/secundario , Teleterapia por Radioisótopo , Estudios Retrospectivos , Resultado del Tratamiento , Neoplasias de la Vejiga Urinaria/secundario , Neoplasias de la Vejiga Urinaria/cirugía , Neoplasias de la Vulva/diagnóstico , Neoplasias de la Vulva/tratamiento farmacológico , Neoplasias de la Vulva/patología , Neoplasias de la Vulva/radioterapia , Neoplasias de la Vulva/cirugía
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