RESUMEN

Inherited coagulopathies are reported in a number of dog breeds. However, to date, there is no report of Weimaraners suffering factor VIII deficiency (haemophilia A). We report the discovery of haemophilia A in both males from a single litter of Weimaraners. Haemophilia A in human beings often results from a de novo stochastic mutation. We found no evidence using currently available screening tests of haemophilia A in relatives as far back as three generations making a stochastic mutation possible in this litter.

Asunto(s)

Enfermedades de los Perros/genética , Hemofilia A/veterinaria , Mutación , Animales , Perros , Factor VIII/genética , Predisposición Genética a la Enfermedad , Hemofilia A/genética , Masculino , Linaje