RESUMEN
We report experimental manipulation of the magnetic states of elliptical cobalt magnetostrictive nanomagnets (with nominal dimensions of â¼340 nm × 270 nm × 12 nm) delineated on bulk 128° Y-cut lithium niobate with acoustic waves (AWs) launched from interdigitated electrodes. Isolated nanomagnets (no dipole interaction with any other nanomagnet) that are initially magnetized with a magnetic field to a single-domain state with the magnetization aligned along the major axis of the ellipse are driven into a vortex state by acoustic waves that modulate the stress anisotropy of these nanomagnets. The nanomagnets remain in the vortex state until they are reset by a strong magnetic field to the initial single-domain state, making the vortex state nonvolatile. This phenomenon is modeled and explained using a micromagnetic framework and could lead to the development of extremely energy efficient magnetization switching methodologies for low-power computing applications.
RESUMEN
Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide. There is an increasing need to develop devices for drug delivery to address ocular diseases. This study focuses on the design, simulation, and development of an implantable ocular drug delivery device consisting of micro-/nanochannels embedded between top and bottom covers with a drug reservoir made from polydimethylsiloxane (PDMS) which is silicon-based organic and biodegradable polymer. Several simulations were carried out with six different micro-channel configurations in order to see the feasibility for ocular drug delivery applications. Based on the results obtained, channel design of osmotic I and osmotic II satisfied the diffusion rates required for ocular drug delivery. Finally, a prototype illustrating the three components of the drug delivery design is presented. In the future, the device will be tested for its functionality and diffusion characteristics.
RESUMEN
We have used a combinatorial gradient technique to map precisely how the terrace structure and microdomain lattice alignment in a thin film of a sphere-forming diblock copolymer are affected by both the thickness of the copolymer film and the height of a series of parallel step edges fabricated on the substrate. We find that for film thicknesses slightly incommensurate with integer numbers of sphere layers, the step edges act as nucleation sites for regions with one more or one fewer layers of spheres. We also find that for our system, the hexagonal lattice formed by a single layer of spheres on the low side of a step edge is aligned along the direction of the step edge only where the film on the high side is sufficiently thin to support only a wetting layer of copolymer material. This work will guide the tuning of film thickness and step height in future studies and applications of graphoepitaxy in block copolymer films.