RESUMEN

Contact sensitivity to ranitidine hydrochloride has been demonstrated in 6 of 8 symptomatic exposed pharmaceutical manufacturing employees; a 7th has been found to be sensitized to ranitidine base. Although closed manufacturing processes diminish the risk of such sensitization, operatives with potential exposure should be made aware of the importance of avoiding skin contact.

Asunto(s)

Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Exposición Profesional/efectos adversos , Ranitidina/efectos adversos , Adulto , Industria Química , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Profesional/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Pruebas del Parche , Medición de Riesgo , Muestreo , Sensibilidad y Especificidad