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J Craniomaxillofac Surg ; 43(1): 175-80, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25491275

RESUMEN

AIMS: The aim of this study was to compare the de novo bone formation ability and osteoconductive effects of three different ß-tricalcium phosphate (ß-TCP) graft materials. The micro-architectural parameters of the newly formed bone tissues were also compared among the different graft materials. MATERIAL AND METHODS: Eight male Swiss domestic pigs were used in the study. Five bony defects were made with a trephine bur. Three of the defects were filled with Cerasorb®, Kasios® and Poresorb®. The fourth defect was filled with an autogenous bone graft. The last defect remained empty. All subjects were sacrificed after 8 weeks. RESULTS: When compared to a negative control group, significant healing was observed in all the groups except the Cerasorb group. The osteoconductivity of the Poresorb group was better than that of the other groups (p < 0.05). The difference in the osteoconductivity of the Kasios and Cerasorb groups was statistically significant (p < 0.05). Comparison of the micro-architectural properties of newly formed bone tissues retrieved from the defects showed that those filled with Poresorb were the best. CONCLUSION: ß-TCP materials show different results in terms of the volume and characteristics of new bone formation, although they have a similar chemical structure.


Asunto(s)
Sustitutos de Huesos/uso terapéutico , Fosfatos de Calcio/uso terapéutico , Osteogénesis/fisiología , Implantes Absorbibles , Animales , Autoinjertos/trasplante , Enfermedades Óseas/cirugía , Médula Ósea/patología , Matriz Ósea/patología , Sustitutos de Huesos/química , Trasplante Óseo/métodos , Fosfatos de Calcio/química , Hueso Frontal/patología , Hueso Frontal/cirugía , Procesamiento de Imagen Asistido por Computador/métodos , Masculino , Ensayo de Materiales , Modelos Animales , Tamaño de la Partícula , Porosidad , Sus scrofa
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