RESUMEN
Shallot virus X is a typical representative of Allexiviruses. The transcription levels of principal genes involved in the RNA silencing in healthy and shallot virus X-infected plants have been quantified by real-time polymerase chain reaction. There is a negative correlation between the reproduction rates of RNA virus and the levels of RNA-dependent RNA polymerase and DCL proteins in roots and leaves of infected plants. These observations indicate that Shallot X virus employs noncanonical ways of overcoming the antiviral defense of the plant by systemic RNA silencing.
Asunto(s)
Flexiviridae/patogenicidad , Enfermedades de las Plantas/virología , Raíces de Plantas/virología , ARN Polimerasa Dependiente del ARN/genética , Células Vegetales/virología , Enfermedades de las Plantas/genética , Raíces de Plantas/genética , Interferencia de ARN , ARN de PlantaRESUMEN
Interrelations of biodegradable poliglicolic and polilactic acid polymers in various proportions implanted in standardized bone defects were evaluated in animal model with 40 Wister line rats. During 10 month follow-up period bone capsule surrounded all implants, but timing of bone formation and bone quality varied significantly being optimal in LactoSorb group. Destructive features of polymers were also seen in implant-bone contact area defined as inflammation, fibrous tissue formation and cell dystrophy.
Asunto(s)
Implantes Absorbibles/efectos adversos , Materiales Biocompatibles/efectos adversos , Sustitutos de Huesos/efectos adversos , Ácido Láctico/efectos adversos , Poliésteres/efectos adversos , Ácido Poliglicólico/efectos adversos , Polímeros/efectos adversos , Animales , Materiales Biocompatibles/química , Sustitutos de Huesos/química , Huesos/efectos de los fármacos , Huesos/patología , Tejido Conectivo/efectos de los fármacos , Tejido Conectivo/patología , Fibrosis , Inflamación/inducido químicamente , Inflamación/patología , Ácido Láctico/química , Ensayo de Materiales , Poliésteres/química , Ácido Poliglicólico/química , Copolímero de Ácido Poliláctico-Ácido Poliglicólico , Polímeros/química , Ratas , Ratas WistarRESUMEN
The article is devoted to the 80th anniversary of the formation of the naval medical science subunit, which is the part of the 1st Central Research Institute of the Defense Ministry of Russian Federation. In the 30th years of XX century, a group of naval doctors formulated the main directions of preventive naval medicine. For eight decades, several generations of medical scientists have developed and ensured implementation of regulatory requirements for habitability and ergonomics of Navy ships. At the present stage, this work focuses on promising directions of the development of the domestic military shipbuilding and the use of advanced and innovative biomedical technologies.
Asunto(s)
Investigación Biomédica/historia , Medicina Militar/historia , Medicina Naval/historia , Aniversarios y Eventos Especiales , Historia del Siglo XX , Historia del Siglo XXI , Humanos , Federación de RusiaRESUMEN
The paper summarizes the results of in vitro and in vivo studies that have proved biocompatibility and medical safety of Ta and Ti-Nb-Ta-bases alloys. According to some in vitro data Ti-Nb-Ta-based alloy possesses certain advantages when comparing to Ta-based. In particular, it contributes to elevation of viability of cellular elements and to definite increase of their adhesive potential.
Asunto(s)
Aleaciones/uso terapéutico , Aleaciones Dentales/uso terapéutico , Implantación Dental , Niobio , Tantalio , Titanio , Aleaciones/efectos adversos , Animales , Células Cultivadas , Aleaciones Dentales/efectos adversos , Fibroblastos , Ensayo de Materiales , ConejosRESUMEN
The article analyzes the features and clinical aspects of implant-retained restorations in the anterior maxilla important for achieving optimal functional and esthetic results.
Asunto(s)
Implantación Dental , Implantes Dentales , Reparación de Restauración Dental , Adulto , Estética Dental , Femenino , Humanos , Masculino , Persona de Mediana Edad , Rehabilitación Bucal , Adulto JovenRESUMEN
The paper analyzes modern approaches to bone density evaluation by planning of dental implantation procedure. Implantation technique in patients with low-density bone creating favorable conditions for osseous integration is described.
Asunto(s)
Densidad Ósea , Implantación Dental Endoósea/métodos , Maxilares/diagnóstico por imagen , Procedimientos Quirúrgicos Ortognáticos , Adulto , Anciano , Tomografía Computarizada de Haz Cónico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto JovenRESUMEN
The perspectives of use of porous polytetrafluorethilen (PTPE) with modified surface combined with mesenchymal stem cells for tissue-engineering constructions were studied. The paper also describes the mode of PTPE surface modification consisting in nanostructured metallic or ceramic layer application resulting in biocompatibility and surface adhesion rates increase. The magnetic atomizing of Ti and Ti-Ca-P-C-O-N nanolayers enhances the material integration potential as well as adhesion rates thus making it perspective when combined with mesenchymal stem cells for bone defects plasty.
Asunto(s)
Materiales Biocompatibles Revestidos , Implantación de Prótesis Maxilofacial , Nanoestructuras , Politetrafluoroetileno , Ingeniería de Tejidos , Andamios del Tejido , Adhesión Celular , Células Cultivadas , Humanos , Células Madre Mesenquimatosas/citología , Células Madre Mesenquimatosas/fisiología , Aleaciones de Cerámica y MetalRESUMEN
The paper describes the sinus-lifting technique useful in patients with alveolar bone deficiency. The technique allows significantly lowering the risk of maxillary sinus mucosa perforation and improves bone tissue regeneration.
Asunto(s)
Pérdida de Hueso Alveolar/cirugía , Aumento de la Cresta Alveolar , Elevación/efectos adversos , Seno Maxilar/lesiones , Mucosa Nasal/lesiones , Adulto , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
It was analyzed the status of dental implants integration into bone tissue problem. The concept of stages and mechanisms of development of integration process in the implant-bone interface based on literature data and own study was presented.
Asunto(s)
Implantación Dental Endoósea , Implantes Dentales , Adaptación Fisiológica , Homeostasis , HumanosRESUMEN
Smooth muscular tissue (SMT) of human urinary system was studied at different levels (renal pelvis, proximal and distal parts of the ureter) in health and some urological diseases (vesicoureteral reflux, ureteral obstruction). The method of target cell dissociation was used. The volume of myocytes, nuclei, nuclear-cytoplasmic correlation were calculated. Content of DNA and cytoplasmic protein was studied cytospectrophotometrically. Electron-microscopic study was also made. Three types of myocytes with different structural-metabolic parameters were detected. There were significant differences in mean volumes of myocytes, cytophotometric indices of SMT in different parts of the urinary tracts related to the pattern of these zones functioning. A comparative analysis of intact and affected SMT of the distal ureter demonstrated changes in the structure of leiomyocytes population, optic density of cytoplasmic protein and proliferative activity of myocytes which correlated depending on the kind and change of functional load.
Asunto(s)
Pelvis Renal/patología , Músculo Liso/patología , Miocitos del Músculo Liso/ultraestructura , Uréter/patología , Enfermedades Urológicas/patología , Adulto , Niño , Preescolar , Citoplasma/química , ADN/análisis , Femenino , Humanos , Pelvis Renal/química , Pelvis Renal/metabolismo , Masculino , Persona de Mediana Edad , Músculo Liso/química , Músculo Liso/metabolismo , Miocitos del Músculo Liso/química , Miocitos del Músculo Liso/metabolismo , Proteínas/análisis , Uréter/química , Uréter/metabolismo , Enfermedades Urológicas/metabolismoRESUMEN
Isocaloric diets supplying about 2900 kcal/kg and based on maize, wheat and barley respectively, were fed to pullets for 13 weeks from point of lay. The number of cases of subclinical fatty liver-haemorrhagic syndrome and the mean total lipid, triglyceride and monoglyceride content of the liver decreased in the above order of diets. The final body weight, weight gain and abdominal fat score followed the order wheat greater than maize greater than barley. Reduction of the energy content of the wheat and barley diets to 2670 and 2490 kcal/kg respectively by the omission of animal fat was associated with a reduction in the lipid content of the liver only in the case of the wheat diets. Egg production and quality were uniformly high and no difference was detected in plasma triglyceride and free fatty acid levels.