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Radiother Oncol ; 102(2): 290-6, 2012 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21962820

RESUMEN

PURPOSE: A new 4D in vivo dosimetry tool, RADPOS, has been used on lung cancer patients to evaluate the feasibility of using the detectors to characterize variations in patient breathing patterns as well as to monitor daily variations in dose. METHODS AND MATERIALS: The RADPOS system combines a MOSFET dosimeter with an electromagnetic positioning sensor for simultaneous measurement of real-time dose and spatial coordinates. Three RADPOS sensors were placed on patients' chest and abdomen during a 4DCT and daily treatments. A fourth detector was also placed on the couch as reference. Position data were collected in real-time and total dose was read at the end of each fraction. RESULTS: Significant deviations in surface motion have been found between the day of 4DCT and treatment fractions in 9 of 10 patients. Variations in daily dose ranged from 2.5 to 13.7 cGy (2.8-14.0%) and results agreed with treatment plan values for all but three points. CONCLUSIONS: Changes in breathing motion have been found that emphasize a need for continued position monitoring. RADPOS measurements can be used to monitor such variations as well as to measure surface dose without any disruption to the treatment schedule or discomfort to patients.


Asunto(s)
Neoplasias Pulmonares/diagnóstico por imagen , Neoplasias Pulmonares/radioterapia , Radiometría/métodos , Planificación de la Radioterapia Asistida por Computador/métodos , Respiración , Tomografía Computarizada por Rayos X/métodos , Anciano , Anciano de 80 o más Años , Fenómenos Electromagnéticos , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Movimiento (Física) , Fantasmas de Imagen , Dosificación Radioterapéutica , Resultado del Tratamiento
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