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Objetivo: Avaliar a efetividade do uso de vídeos para a implementação de protocolos de reabilitação entre a equipe multiprofissional durante o manejo dos pacientes com Doença de Parkinson. Métodos: Foi conduzida uma revisão integrativa da literatura a partir da pergunta norteadora, usando os elementos do PICO para identificar os descritores de assunto e sinônimos para as bases de dados Cochrane Library (CENTRAL), LILACS, PubMed, Education Resources Information Center (ERIC). Foi planejado incluir estudos que avaliaram a ferramenta de vídeo como estratégia de desenvolvimento da equipe multiprofissional que atua na reabilitação do paciente com Doença de Parkinson, independentemente do ano e do idioma de publicação. A avaliação crítica da literatura também foi planejada para todos os estudos incluídos. Resultados: Nenhum estudo atendeu ao critério de inclusão desta revisão e por isso os autores decidiram discutir e relatar uma síntese dos estudos semelhantes, com potencial para a inclusão, do tema abordado na pergunta norteadora. Assim, um total de dez estudos foram sintetizados em quadros. Conclusão: Não foi possível identificar a efetividade da intervenção estudada devido à ausência de estudos clínicos com essa finalidade. Entretanto, foram avaliados estudos semelhantes para aprimorar o delineamento de um possível estudo clínico.

Objective: To evaluate the effectiveness of using videos for the implementation of rehabilitation protocols among the multidisciplinary team during the management of patients with Parkinson's disease. Methods: An integrative literature review was conducted based on the guiding question, using PICO elements to identify subject descriptors and synonyms for the Cochrane Library (CENTRAL), LILACS, PubMed, Education Resources Information Center) databases. It was planned to include studies that evaluated the video tool as a development strategy for the multidisciplinary team that works in the rehabilitation of patients with Parkinson's disease, regardless of the year and language of publication. Critical literature review was also planned for all included studies. Results: No study met the inclusion criteria of this review and therefore the authors decided to discuss and report a synthesis of similar studies, with potential for inclusion, of the topic addressed in the guiding question. Thus, a total of ten studies were summarized in tables. Conclusion: It was not possible to identify the effectiveness of the intervention studied due to the lack of clinical studies with this purpose. However, similar studies were evaluated to improve the design of a possible clinical study.

Objetivo: Evaluar la efectividad del uso de videos para la implementación de protocolos de rehabilitación entre el equipo multidisciplinario durante el manejo de pacientes con enfermedad de Parkinson. Métodos: Se realizó una revisión integrativa de la literatura basada en la pregunta guía, utilizando elementos PICO para identificar descriptores para las bases de datos Cochrane Library (CENTRAL), LILACS, PubMed, Education Resources Information Center (ERIC). Se planeó incluir estudios que evaluaran la herramienta de video como estrategia de desarrollo para el equipo multidisciplinario que trabaja en la rehabilitación de pacientes con enfermedad de Parkinson, independientemente del año e idioma de publicación. También se planeó una revisión crítica de la literatura para todos los estudios incluidos. Resultados: Ningún estudio cumplió con los criterios de inclusión de esta revisión y, por lo tanto, los autores decidieron discutir e informar una síntesis de estudios similares, con potencial de inclusión, del tema abordado en la pregunta guía. Por lo tanto, un total de diez estudios se resumieron en tablas. Conclusión: No fue posible identificar la efectividad de la intervención estudiada debido a la falta de estudios clínicos con este fin. Sin embargo, se evaluaron estudios similares para mejorar el diseño de un posible estudio clínico.

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Acanthamoeba spp. have always caused disease in immunosuppressed patients, but since 1986, they have become a worldwide public health issue by causing infection in healthy contact lens wearers. Amoebae of the Acanthamoeba genus are broadly distributed in nature, living either freely or as parasites, and are frequently associated with biofilms throughout the environment. These biofilms provide the parasite with protection against external aggression, thus favoring its increased pathogeny. This review aims to assess observational studies on the association between Acanthamoeba spp. and biofilms, opening potential lines of research on this severe ocular infection. A systematic literature search was conducted in May 2020 in the following databases: PubMed Central®/Medline, LILACS, The Cochrane Library, and EMBASE®. The studies were selected following the inclusion and exclusion criteria specifically defined for this review. Electronic research recovered 353 publications in the literature. However, none of the studies met the inclusion criterion of biofilm-producing Acanthamoeba spp., inferring that the parasite does not produce biofilms. Nonetheless, 78 studies were classified as potentially included regarding any association of Acanthamoeba spp. and biofilms. These studies were allocated across six different locations (hospital, aquatic, ophthalmic and dental environments, biofilms produced by bacteria, and other places). Acanthamoeba species use biofilms produced by other microorganisms for their benefit, in addition to them providing protection to and facilitating the dissemination of pathogens residing in them.

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OBJETIVO: Avaliar o grau de independência funcional, por meio das Atividades Básicas de Vida Diária, entre idosos usuários de um centro de saúde. MÉTODOS: Estudo do tipo transversal e descritivo, realizado no Centro de Saúde Escola do Marco, em Belém (PA). A coleta de dados foi feita por meio de dois protocolos de pesquisa: um de dados pessoais e um contendo perguntas sobre as Atividades Básicas de Vida Diária, de acordo com o índice de Katz. A coleta de dados foi realizada de forma aleatória às terças, quartas e sextas-feiras. Foram pesquisados 165 idosos. As Atividades Básicas de Vida Diária foram avaliadas pelo índice de Katz. Para análise estatística, foram utilizados os testes não paramétricos qui quadrado e G de independência. RESULTADOS: Houve correlação significativa entre nível de dependência e diabetes mellitus, prática de atividades físicas e Atividades Básicas de Vida Diária. Dentre os idosos, 69,7% foram considerados independentes, sendo 69,09% alocados na classificação A da escala, 24,85% como B, 0,61% como C e 5,45% em outras classificações. A Atividade Básica de Vida Diária que mais apresentou idosos dependentes foi a relacionada a continência. CONCLUSÃO: A maioria dos idosos pesquisados é independente para as Atividades Básicas de Vida Diária.

OBJECTIVE: To evaluate functional independence degree among elderly users of a healthcare center through their Activities of daily living (ADL). METHODS: This is a crosssectional, descriptive study performed at Centro de Saúde Escola do Marco, in the city of Belem (PA, Brazil). Data collection was performed through two research protocols: one containing personal information, and the other containing questions about participants' ADL, according to Katz Index. Data collection was randomly performed on Tuesdays, Wednesdays and Fridays. A total of 165 elderly participated in this study. Activities of daily living were analyzed according to Katz Index. For statistical analysis, Chi-square test, and G-test of independency were used. RESULTS: There was a significant correlation betweenthe dependence degree and diabetes mellitus, physical activities practices and Activities of daily living. Among the elderly, 69,7% were classified as independent, with 69,09% being allocated in classification A of the Index, 24,85% in B, 0,61% in C, and 5,45% in others classifications. The Activity of daily living that was mostly related to dependent elderly was continence. CONCLUSIONS: Most of the surveyed elderly were independent for Activities of daily living.

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BACKGROUND: Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disease that involves the exocrine glands and internal organs. pSS leads to destruction and loss of secretory function due to intense lymphoplasmacytic infiltration. Therapeutic options include mainly symptomatic and supportive measures, and traditional immunosuppressant drugs have shown no effectiveness in randomized trials. Rituximab (RTX) is a chimeric antibody anti-CD20 that leads to B cell depletion by diverse mechanisms. There is evidence that this drug may be effective for treating pSS. The objective of this systematic review was to evaluate Rituximab effectiveness and safety for treating pSS. METHODS AND FINDINGS: We conducted a systematic review of RCTs published until December 2015, with no language restriction. We registered a protocol on Plataforma Brasil (40654814.6.0000.5505) and developed search strategies for the following scientific databases: MEDLINE, EMBASE, CENTRAL and LILACS. We included adults with established pSS diagnosis and considered the use of Rituximab as intervention and the use of other drugs or placebo as control. Four studies met our eligibility criteria: three with low risk of bias and one with uncertain risk of bias. The total number of participants was 276 (145 RTX, 131 placebo). We assessed the risk of bias of each included study and evaluated the following as primary outcomes: lacrimal gland function, salivary gland function, fatigue improvement and adverse events. We found no significant differences between the groups in the Schirmer test at week 24 meta-analysis (MD 3.59, 95% CI -2.89 to 10.07). Only one study evaluated the lissamine green test and reported a statistically significant difference between the groups at week 24 (MD -2.00, 95% CI -3.52 to -0.48). There was a significant difference between the groups regarding salivary flow rate (MD 0.09, 95% CI 0.02 to 0.16) and improvement in fatigue VAS at weeks 6 (RR 3.98, 95% CI 1.61 to 9.82) and week 16 (RR 3.08, 95% CI 1.21 to 7.80). CONCLUSIONS: According to moderate quality evidence, the treatment with a single RTX course in patients with SSp presents discrete effect for improving lacrimal gland function. Low-quality evidence indicates the potential of this drug for improving salivary flow. According to low quality evidence, no differences were observed in the evaluation after 24 weeks regarding fatigue reduction (30% VAS), serious adverse events occurrence, quality of life improvement and disease activity. With a very low level of evidence, there was no improvement in oral dryness VAS evaluation.

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