RESUMEN

In this report new hybrid materials based on brushite-alginate and monetite-alginate were prepared by self-assembling alginate chains and phosphate source ions via a gelation process with calcium ions. The alginate served as nanoreactor for nucleation and growth of brushite or/and monetite due to its gelling and swelling properties. The alginate gel framework, the crystalline phase and morphology of formed hybrid biomaterials were shown to be strongly dependent upon the concentration of the phosphate precursors. These materials were characterized by thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive x-ray analysis (EDX).

Asunto(s)

Alginatos/química , Materiales Biomiméticos/síntesis química , Biomimética/métodos , Fosfatos de Calcio/química , Cristalización/métodos , Diseño de Fármacos , Ácido Glucurónico/química , Ácidos Hexurónicos/química , Sustancias Macromoleculares/química , Ensayo de Materiales , Microesferas , Conformación Molecular , Tamaño de la Partícula , Propiedades de Superficie