RESUMEN
In view of the comparative frequency of posterior dislocations of the elbow, it is rather remarkable that anterior dislocations of that joint should be among the rarest of injuries [1]. Our case is one of the first cases of anterior dislocation of the elbow without any periarticular fracture or pre-existing deformities around the elbow [2].
Asunto(s)
Lesiones de Codo , Luxaciones Articulares/etiología , Luxaciones Articulares/terapia , Manipulación Ortopédica , Femenino , Humanos , Luxaciones Articulares/diagnóstico por imagen , Luxaciones Articulares/rehabilitación , Persona de Mediana Edad , Radiografía , Resultado del TratamientoRESUMEN
Lipomas are rarely localized at the hand, and more unfrequently at the anatomical snuffbox. We report a case of a lipoma that compressed the lateral branch of the superficial sensory branch of the radial nerve.
Asunto(s)
Mano , Lipoma/complicaciones , Síndromes de Compresión Nerviosa/etiología , Nervio Radial , Adulto , Humanos , Lipoma/cirugía , Masculino , Síndromes de Compresión Nerviosa/cirugíaRESUMEN
Bone metastases in the hand are rare. The authors report a case of a 46-year-old woman diagnosed with a giant hand tumor, revealing a lung adenocarcinoma. An amputation of the thumb was performed. Histology confirmed a metastasis from the lung adenocarcinoma.
Asunto(s)
Adenocarcinoma/secundario , Neoplasias Óseas/secundario , Neoplasias de los Bronquios/patología , Pulgar/patología , Adenocarcinoma/diagnóstico , Adenocarcinoma/cirugía , Adulto , Amputación Quirúrgica , Neoplasias Óseas/diagnóstico , Neoplasias Óseas/cirugía , Neoplasias de los Bronquios/cirugía , Femenino , Humanos , Pulgar/cirugía , Resultado del TratamientoRESUMEN
The authors report in the treatment of fractures of the proximal phalanx of the fingers, the use of Eiffel Tower pinning, a relatively simple method, fast and stable, associated to a protection and early rehabilitation. The objective of this method is to offer to the patient a pollici-digital grip. Our study is a retrospective study of 45 patients treated for fractures of the proximal phalanx of the fingers by percutaneous pinning according to Eiffel Tower method. We detail this simple and economic technique and examine the functional and radiological results of this series of patients. The amplitude of the active total motion of the proximal interphalangeal joint is on average 94.16 degrees (78.5 % of the normal active mobility of the proximal interphalangeal joint), and the amplitude of the active total motion of the metacarpo-phalangeal joint is on average 90.05 degrees (75 % of the normal active mobility of the metacarpo-phalangeal joint).
Asunto(s)
Clavos Ortopédicos , Falanges de los Dedos de la Mano , Fijación Interna de Fracturas/métodos , Fracturas Óseas/cirugía , Accidentes por Caídas/estadística & datos numéricos , Accidentes de Trabajo/estadística & datos numéricos , Accidentes de Tránsito/estadística & datos numéricos , Adolescente , Adulto , Traumatismos en Atletas/complicaciones , Femenino , Falanges de los Dedos de la Mano/lesiones , Falanges de los Dedos de la Mano/cirugía , Fijación Interna de Fracturas/instrumentación , Curación de Fractura , Fracturas Óseas/diagnóstico por imagen , Fracturas Óseas/etiología , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Rango del Movimiento Articular , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
Volar perilunar dislocations of the carpus are rare. They occur in young patients following a violent injury. Open reduction is often needed because of instability of the lesion. The authors report a case of volar transscaphoid perilunate fracture-dislocation treated surgically, with a satisfactory functional result after a follow-up of two and a half years.
Asunto(s)
Articulaciones del Carpo/lesiones , Fracturas Óseas , Luxaciones Articulares , Hueso Semilunar/lesiones , Hueso Escafoides/lesiones , Adulto , Articulaciones del Carpo/cirugía , Fracturas Óseas/cirugía , Humanos , Luxaciones Articulares/cirugía , Hueso Semilunar/cirugía , Masculino , Hueso Escafoides/cirugíaRESUMEN
The authors report an unusual case of multiple carpometacarpal joint dislocations of the ulnar four fingers, treated by closed reduction and fixation with percutaneous Kirschner-wires. A plaster splint with the wrist in neutral position was applied for six weeks. Active physiotherapy of the fingers was started from four weeks after surgery, with a satisfactory result.
Asunto(s)
Articulaciones Carpometacarpianas/lesiones , Luxaciones Articulares/terapia , Accidentes de Tránsito , Adulto , Articulaciones Carpometacarpianas/diagnóstico por imagen , Humanos , Luxaciones Articulares/diagnóstico por imagen , Masculino , Manipulación Ortopédica , Radiografía , Férulas (Fijadores)RESUMEN
Echinococcosis is a widespread zoonosis which is endemic in most sheep-raising countries. Primary isolated muscular localisation is uncommon even in these endemic areas. The authors report a rare case of primary hydatid cyst localized in the myotendinous junction of the flexor digitorum profundus. According to our review of the medical literature, there are no reports of a similar case, making ours the first such report.
Asunto(s)
Equinococosis/diagnóstico , Enfermedades Musculares/diagnóstico , Enfermedades Musculares/parasitología , Adulto , Albendazol/uso terapéutico , Antiprotozoarios/uso terapéutico , Equinococosis/terapia , Femenino , Antebrazo , Humanos , Enfermedades Musculares/terapiaRESUMEN
The authors report a series of six cases of acute traumatic dislocation of the trapeziometacarpal joint of the thumb. Displacement was always dorso-radial. There were associated osseous lesions in one patient: avulsion of the palmar tubercle of the base of the first metacarpal with a fracture of the trapezoid. All the patients were treated immediately by percutaneous pinning according to the technique of Wiggins. The late results, evaluated at an average of 19 months postinjury (range: 8-29 months), were considered to be satisfactory in the majority of the patients. Treatment by percutaneous pinning remains a less sophisticated alternative that in our experience yields consistently good results, provided there is no preexisting degenerative articular lesion.
Asunto(s)
Clavos Ortopédicos , Fijación Interna de Fracturas/métodos , Luxaciones Articulares/cirugía , Metacarpo/cirugía , Pulgar/lesiones , Hueso Trapecio/cirugía , Hueso Trapezoide/cirugía , Enfermedad Aguda , Adulto , Femenino , Estudios de Seguimiento , Humanos , Masculino , Articulación Metacarpofalángica/cirugía , Metacarpo/lesiones , Persona de Mediana Edad , Rango del Movimiento Articular , Estudios Retrospectivos , Hueso Trapecio/lesiones , Hueso Trapezoide/lesiones , Resultado del TratamientoRESUMEN
The actin genes of Trypanosoma brucei are transcribed constitutively during the parasite life-cycle, by a polymerase sensitive to alpha-amanitin. The start region of the actin gene transcription unit was mapped by virtue of the accumulation of promoter-proximal transcripts which occurs following moderate UV irradiation. This region, located about 4 kilobases upstream from the genes, was able to direct transient expression of the bacterial Chloramphenicol Acetyl Transferase (CAT) gene in both bloodstream and procyclic forms of the parasite. The essential region of the promoter was defined by deletion, and appeared to be within 600 bp upstream from the putative transcription start site. It does not share significant homology with the other trypanosome promoters described so far (VSG, procyclin, rDNA), which all direct alpha-amanitin resistant transcription.
Asunto(s)
Actinas/genética , Regiones Promotoras Genéticas/genética , Trypanosoma brucei brucei/genética , Amanitinas/farmacología , Animales , Secuencia de Bases , Northern Blotting , Southern Blotting , Cloranfenicol O-Acetiltransferasa/genética , Deleción Cromosómica , Clonación Molecular , Análisis Mutacional de ADN , Estimulación Eléctrica , Cinética , Datos de Secuencia Molecular , Plásmidos/genética , Transcripción Genética/efectos de los fármacos , Transcripción Genética/fisiología , Trypanosoma brucei brucei/crecimiento & desarrolloRESUMEN
In Trypanosoma brucei, the actin gene is present in a cluster of two, three, or four tandemly linked copies, depending on the strain. Each cluster seems to exist in two allelic versions, as suggested by the polymorphism of both gene number and restriction fragment length in the DNA from cloned trypanosomes. The amplification of the gene copy number probably occurs through unequal sister chromatid exchange. The chromosomes harboring the actin genes belong to the large size class. The coding sequence was 1,128 nucleotides long and showed 60 to 70% homology to other eucaryotic actin genes. Surprisingly, this homology seemed weaker with Trypanosoma congolense, Trypanosoma cruzi, Trypanosoma vivax, Trypanosoma mega, or Leishmania actin-specific sequences. The mRNA was around 1.6 kilobases long and was synthesized at the same level in bloodstream and procyclic forms of the parasite. Large RNA precursors, up to 7.7 kilobases, were found in a pattern identical in strains containing either two or three gene copies. Probing of the flanking regions of the gene with either steady-state or in vitro transcripts, as well as S1 nuclease protection and primer extension experiments, allowed mapping of the 3' splice site of the actin mRNA, 38 nucleotides upstream from the translation initiation codon. A variably sized poly(dT) tract was found about 30 base pairs ahead of the splice site. The largest detected actin mRNA precursor seemed to give rise to at least two additional stable mRNAs. The RNA polymerase transcribing the actin gene exhibited the same sensitivity to inhibition by alpha-amanitin as that transcribing both the spliced leader and the bulk of polyadenylated mRNAs.