RESUMEN
The aim of this study was to determine the relative importance of gestational diabetes (GD) risk factors to identify populations at risk. A total of 400 pregnant patients were studied, 200 with confirmed GD diagnosis and 200 controls with risk factors. They regularly attended health-care units belonging to the Ministry of Health of the Province of Buenos Aires, in the context of the Program for the Prevention, Care and Treatment of People with Diabetes of the Province of Buenos Aires (PRODIABA). The following risk factors were evaluated: GD in previous pregnancies, history of diabetes in first degree relatives, age > or = 30 years, BMI > 26, history of fetal macrosomy, perinatal mortality and hypertension during pregnancy. Data analysis was performed with the Program of Statistics in Public Health Epilnfo 6. The association between GD development as a dependent variable and the presence of different risk factors (independent variables) was analyzed with a multiple logistic regression model, determining the logistic probability to develop GD. Results showed that the incidence of risk factors to develop GD is not the same; therefore, they do not have the same predictive value. Overweight or obesity played a key central role, not only for its frequency, but also for its contribution to GD development. Our findings reinforce the importance of multi causal studies as the basis to design and implement prevention strategies for diabetes.
Asunto(s)
Diabetes Gestacional/etiología , Adulto , Argentina/epidemiología , Estudios de Casos y Controles , Diabetes Gestacional/epidemiología , Diabetes Gestacional/prevención & control , Femenino , Humanos , Modelos Logísticos , Análisis Multivariante , Obesidad/complicaciones , Oportunidad Relativa , Embarazo , Estudios Retrospectivos , Factores de RiesgoRESUMEN
The aim of this study was to determine the relative importance of gestational diabetes (GD) risk factors to identify populations at risk. A total of 400 pregnant patients were studied, 200 with confirmed GD diagnosis and 200 controls with risk factors. They regularly attended health-care units belonging to the Ministry of Health of the Province of Buenos Aires, in the context of the Program for the Prevention, Care and Treatment of People with Diabetes of the Province of Buenos Aires (PRODIABA). The following risk factors were evaluated: GD in previous pregnancies, history of diabetes in first degree relatives, age > or = 30 years, BMI > 26, history of fetal macrosomy, perinatal mortality and hypertension during pregnancy. Data analysis was performed with the Program of Statistics in Public Health Epilnfo 6. The association between GD development as a dependent variable and the presence of different risk factors (independent variables) was analyzed with a multiple logistic regression model, determining the logistic probability to develop GD. Results showed that the incidence of risk factors to develop GD is not the same; therefore, they do not have the same predictive value. Overweight or obesity played a key central role, not only for its frequency, but also for its contribution to GD development. Our findings reinforce the importance of multi causal studies as the basis to design and implement prevention strategies for diabetes.
Asunto(s)
Diabetes Mellitus Tipo 2/clasificación , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/complicaciones , Diabetes Mellitus Tipo 2/terapia , Diabetes Mellitus Tipo 2/patología , Diabetes Mellitus Tipo 2/prevención & control , Diabetes Mellitus Tipo 2/economía , Diabetes Mellitus Tipo 2/dietoterapia , Nefropatías Diabéticas , Retinopatía Diabética , Neuropatías Diabéticas , Pie Diabético , Hiperlipidemias/etiología , Diabetes Gestacional , Educación del Paciente como Asunto , Dieta para DiabéticosAsunto(s)
Diabetes Gestacional , /clasificación , /complicaciones , /diagnóstico , /dietoterapia , /economía , /patología , /prevención & control , /terapia , Dieta para Diabéticos , Educación del Paciente como Asunto , Hiperlipidemias/etiología , Nefropatías Diabéticas , Neuropatías Diabéticas , Pie Diabético , Retinopatía DiabéticaRESUMEN
Se estudiaron los cambios ocurridos a nivel clínico, bioquímico e inmunológico en pacientes diabéticos insulinodependientes (adultos y niños) tratados con insulina NPH de origen porcino (Biobras) durante 90 días y se loscomparó con los obtenidos previamente en esos mismos pacientes tratados con otras insulinas disponibles en el mercado nacional. Los resultados obtenidos no mostraron cambios importantes en el corto plazo en ninguno de los parámetros estudiados, lo que sugiere que la insulina Biobras presenta características apropiadas para el tratamiento del diabético insulinodependiente. Ello brinda al paciente, junto con una correcta alimentación, una actividad física apropiada y el permanente soporte educativo, otra alternativa de elección para el tratamiento insulínico de esta enfermedad metabólica
Asunto(s)
Humanos , Diabetes Mellitus Tipo 1 , InsulinaRESUMEN
Se estudiaron los cambios ocurridos a nivel clínico, bioquímico e inmunológico en pacientes diabéticos insulinodependientes (adultos y niños) tratados con insulina NPH de origen porcino (Biobras) durante 90 días y se loscomparó con los obtenidos previamente en esos mismos pacientes tratados con otras insulinas disponibles en el mercado nacional. Los resultados obtenidos no mostraron cambios importantes en el corto plazo en ninguno de los parámetros estudiados, lo que sugiere que la insulina Biobras presenta características apropiadas para el tratamiento del diabético insulinodependiente. Ello brinda al paciente, junto con una correcta alimentación, una actividad física apropiada y el permanente soporte educativo, otra alternativa de elección para el tratamiento insulínico de esta enfermedad metabólica (AU)