RESUMEN
Interstitial nephritis and immune complex-mediated glomerulonephritis are the two common renal manifestations of primary Sjögren's syndrome (SS). Here, we discuss three cases of primary SS where presenting manifestation was distal renal tubular acidosis. The possibility of an underlying autoimmune disorder should be considered in a patient presenting with distal tubular acidosis or recurrent hypokalemic periodic paralysis as treatment of primary disease improves the outcome of illness.
Asunto(s)
Acidosis Tubular Renal/inmunología , Parálisis Periódica Hipopotasémica/inmunología , Síndrome de Sjögren/inmunología , Acidosis Tubular Renal/diagnóstico , Acidosis Tubular Renal/tratamiento farmacológico , Adulto , Biopsia , Suplementos Dietéticos , Femenino , Humanos , Hidroxicloroquina/uso terapéutico , Parálisis Periódica Hipopotasémica/diagnóstico , Parálisis Periódica Hipopotasémica/tratamiento farmacológico , Túbulos Renales Distales/inmunología , Túbulos Renales Distales/patología , Potasio/uso terapéutico , Recurrencia , Glándulas Salivales/inmunología , Glándulas Salivales/patología , Síndrome de Sjögren/complicaciones , Síndrome de Sjögren/diagnóstico , Síndrome de Sjögren/tratamiento farmacológico , Esteroides/uso terapéutico , Resultado del TratamientoRESUMEN
Renal complications due to organophosphate poisoning are very rare. We are presenting a unique case of transient distal renal tubular acidosis due to organophosphate poisoning, which to the best of our knowledge is the first of its kind. An elderly female after deliberate self-harm with ingestion of chlorpyrifos had multiple ventricular arrhythmias due to hypokalemia secondary to distal renal tubular acidosis which improved completely after treatment.