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1.
Cureus ; 16(3): e57299, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38690479

RESUMEN

Lichen planus (LP) is a common T-cell-mediated autoimmune skin disease, and its exact etiology is unknown. Typically, it affects the trunk, flexural surfaces, and the mucosa.We report a rare finding of LP involving both eyelids in a 67-year-old female. A 67-year-old Saudi female with a medical history of diabetes mellitus, hypothyroidism and rheumatoid arthritis presented with a three-month history of pruritic skin eruptions in both eyelids. She had no associated musculoskeletal symptoms or fatigue and no medical or family history of atopy. The patient had violaceous, thin, scaly plaques confined to both eyelids. Oral mucosa, genitalia, scalp, and nails were not affected. Histopathology from the right lower eyelid confirmed the diagnosis of LP. Hepatitis C virus serology was negative. Patient was examined by ophthalmology to rule out conjunctival involvement of LP. She had dry eyes only. She was initially managed by topical tacrolimus 0.1% ointment and didn't tolerate it due to severe reaction. She tolerated mometasone propionate 0.1% cream, which relieved the itch and partially improved the lesions. Although rare, LP of the eyelids must be considered among differential diagnoses of eyelid dermatitis. It can be confined, or it may concomitantly involve other parts of the body. LP of the eyelid may also extend to the conjunctiva, so it's important to screen patients by ophthalmology to rule out possible ocular involvement. This is the first case report of a Saudi patient with LP confined to the eyelid. The management of LP involving the eyelids is challenging. Treatment options include topical steroids, tacrolimus ointment, phototherapy and oral retinoids (etretinate).

2.
Cureus ; 15(11): e48600, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-38084180

RESUMEN

Introduction The human papillomavirus (HPV) causes the most sexually transmitted infections (STIs) worldwide. According to the World Health Organization (WHO), cervical cancer is the fourth most common type of cancer among women worldwide and the eighth leading cause of female cancer death in Saudi Arabia, especially in women between the ages of 15 and 44. The HPV vaccine is known to prevent HPV disease and death. Because parents are often the decision-makers regarding receiving HPV vaccination during adolescence, assessing parents' knowledge about HPV and its relationship with their intention to vaccinate their daughters is highly necessary. Materials and methods An exploratory descriptive cross-sectional study design was used. A total of 773 parents, both mothers and fathers, of female students attending sixth grade from all areas of Jeddah city in Saudi Arabia were recruited. A self-administered validated questionnaire was used to collect the necessary data. Results The current study findings showed that 356 (46.1%) parents had poor knowledge about HPV, 119 (15.4%) had a fair level of knowledge, and 298 (38.5%) had a good level of knowledge. While 344 (44.5%) had intention to vaccinate, 337 (43.6%) were not sure and 92 (11.9%) were not intending to vaccinate. A significant association was identified between knowledge level and respondents' variables such as being the father or mother, nationality, age, educational level, sector of employment, and monthly income. Employment status was significantly associated with the intention to vaccinate against HPV. Conclusion Concerns about the effectiveness and safety of the HPV vaccine as well as lack of knowledge about HPV and the vaccine influenced parents' negative intention to obtain the vaccine. Health promotion initiatives for the HPV vaccine should be culturally responsive and emphasize the risks and benefits of the vaccine for women. Knowledge and attitudes about HPV can be improved through concise, visually designed, and comprehensive educational intervention programs targeting parents and their children at schools. Despite the proven safety and efficacy of HPV vaccines, more comprehensive strategies may be needed in the future to increase coverage rates of HPV vaccination nationwide.

3.
Cureus ; 15(7): e41986, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37593272

RESUMEN

BACKGROUND:  Paranasal sinus mucoceles are epithelium-lined cystic masses usually resulting from obstruction of sinus ostia. They most frequently occur in the frontal and ethmoid sinuses. The etiology is not clarified, but the most common identifiable cause of mucoceles following functional endoscopic sinus surgery (FESS), trauma, neoplasms, and allergy. The clinical symptoms of mucocele vary and are not specific, the most common being ophthalmic symptoms and headache, impinging on adjacent orbital structures, and causing ophthalmic sequelae such as double vision, commonly followed by orbital swelling, epiphora, proptosis, and ptosis. All patients in this study had frontal and frontoethmoidal mucocele and initially complained of frontal headache and ophthalmic symptoms. Definitive treatment options for paranasal sinus mucoceles include external approaches and endoscopic marsupialization.  Objective: The study aimed to identify the etiology, clinical presentation, most common para nasal sinus affected by mucocele, management, and the rate of recurrence in eight cases with mucocele of the paranasal sinuses. METHODS:  Eight patients diagnosed with mucocele of the paranasal sinuses were admitted to our institution between 2014 and 2021. There were two females and six males aged between 14 and 67. Initial symptoms, duration, clinical presentation upon admission, location of the mucocele, type of surgical intervention, and outcome have all been studied.  Results: The most common symptoms at diagnosis were orbital involvement, retrobulbar, and frontal headache. Most patients were diagnosed with frontal mucocele (40%), and three were frontoethmoidal mucocele at the time of presentation. The rest of the cases were diagnosed with ethmoidal mucocele (25%). The etiology was identified in four patients and was unclear in the rest. All patients underwent endoscopic sinus surgery. The most identifiable postoperative complication was a headache. CONCLUSIONS:  The endonasal endoscopic approach is a safe and effective treatment for paranasal sinus mucocele and provides adequate drainage with a low recurrent rate.

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