RESUMEN
The medical and healthcare domains require automatic diagnosis systems (ADS) for the identification of health problems with technological advancements. Biomedical imaging is one of the techniques used in computer-aided diagnosis systems. Ophthalmologists examine fundus images (FI) to detect and classify stages of diabetic retinopathy (DR). DR is a chronic disease that appears in patients with long-term diabetes. Unattained patients can lead to severe conditions of DR, such as retinal eye detachments. Therefore, early detection and classification of DR are crucial to ward off advanced stages of DR and preserve the vision. Data diversity in an ensemble model refers to the use of multiple models trained on different subsets of data to improve the ensemble's overall performance. In the context of an ensemble model based on a convolutional neural network (CNN) for diabetic retinopathy, this could involve training multiple CNNs on various subsets of retinal images, including images from different patients or those captured using distinct imaging techniques. By combining the predictions of these multiple models, the ensemble model can potentially make more accurate predictions than a single prediction. In this paper, an ensemble model (EM) of three CNN models is proposed for limited and imbalanced DR data using data diversity. Detecting the Class 1 stage of DR is important to control this fatal disease in time. CNN-based EM is incorporated to classify the five classes of DR while giving attention to the early stage, i.e., Class 1. Furthermore, data diversity is created by applying various augmentation and generation techniques with affine transformation. Compared to the single model and other existing work, the proposed EM has achieved better multi-class classification accuracy, precision, sensitivity, and specificity of 91.06%, 91.00%, 95.01%, and 98.38%, respectively.
RESUMEN
Medical IoT devices are rapidly becoming part of management ecosystems for pandemics such as COVID-19. Existing research shows that deep learning (DL) algorithms have been successfully used by researchers to identify COVID-19 phenomena from raw data obtained from medical IoT devices. Some examples of IoT technology are radiological media, such as CT scanning and X-ray images, body temperature measurement using thermal cameras, safe social distancing identification using live face detection, and face mask detection from camera images. However, researchers have identified several security vulnerabilities in DL algorithms to adversarial perturbations. In this article, we have tested a number of COVID-19 diagnostic methods that rely on DL algorithms with relevant adversarial examples (AEs). Our test results show that DL models that do not consider defensive models against adversarial perturbations remain vulnerable to adversarial attacks. Finally, we present in detail the AE generation process, implementation of the attack model, and the perturbations of the existing DL-based COVID-19 diagnostic applications. We hope that this work will raise awareness of adversarial attacks and encourages others to safeguard DL models from attacks on healthcare systems.
RESUMEN
Recent advancements in the Internet of Health Things (IoHT) have ushered in the wide adoption of IoT devices in our daily health management. For IoHT data to be acceptable by stakeholders, applications that incorporate the IoHT must have a provision for data provenance, in addition to the accuracy, security, integrity, and quality of data. To protect the privacy and security of IoHT data, federated learning (FL) and differential privacy (DP) have been proposed, where private IoHT data can be trained at the owner's premises. Recent advancements in hardware GPUs even allow the FL process within smartphone or edge devices having the IoHT attached to their edge nodes. Although some of the privacy concerns of IoHT data are addressed by FL, fully decentralized FL is still a challenge due to the lack of training capability at all federated nodes, the scarcity of high-quality training datasets, the provenance of training data, and the authentication required for each FL node. In this paper, we present a lightweight hybrid FL framework in which blockchain smart contracts manage the edge training plan, trust management, and authentication of participating federated nodes, the distribution of global or locally trained models, the reputation of edge nodes and their uploaded datasets or models. The framework also supports the full encryption of a dataset, the model training, and the inferencing process. Each federated edge node performs additive encryption, while the blockchain uses multiplicative encryption to aggregate the updated model parameters. To support the full privacy and anonymization of the IoHT data, the framework supports lightweight DP. This framework was tested with several deep learning applications designed for clinical trials with COVID-19 patients. We present here the detailed design, implementation, and test results, which demonstrate strong potential for wider adoption of IoHT-based health management in a secure way.
RESUMEN
Interoperability is one of the most challenging concerns that face healthcare information system (HIS) actors. Interoperability implementation in this context may be a data exchange interfacing, a service oriented interaction or even a composition of new composite healthcare processes. In fact, optimizing efforts of interoperability achievement is a key requirement to effectively setup, develop and evolve intra- and interorganizational collaboration. To ensure interoperability project effectiveness, this paper proposes a modeling representation of health processes interoperability evolution. Interoperability degrees of involved automated processes are assessed using a ratio metric, taking into account all significant aspects, such as potentiality, compatibility and operational performance. Then, a particle swarm optimization algorithm (PSO) is used as a heuristic optimization method to find the best distribution of effort needed to establish an efficient healthcare collaborative network.