RESUMEN
The article deals with the problem of myocardial damage of various genesis in patients of the intensive care unit and intensive care unit of various age groups. The study included patients with various pathologies with significant manifestations of multiple organ failure and high risks of adverse outcomes. Parametric (Student's t-test) and nonparametric (Mann-Whitney U-test, Pearson's χ2 criterion) statistical methods were used to analyze the severity of the inflammatory response, organ dysfunction, and the need for replacement therapy, in particular ventilator and vasopressor support in patients of different age groups. The frequency of myocardial damage was studied on the basis of an increase in cardiac troponin in patients of the intensive care unit. A comparison of the increase in troponin with morphological changes of the heart was carried out based on the analysis of ECHO, coronary angiography and sectional material. The role of cardiac troponin in the prognosis of adverse events in patients of different ages was analyzed. As a result of the study, it was found that the degree of severity of organ dysfunction, inflammatory response and the need for replacement therapy significantly prevail in elderly patients, as well as the phenomenon of myocardial damage. The main proportion of myocardial lesions was nonspecific. At the same time, the very fact of an increase in cardiac troponin in patients of the intensive care unit is an independent risk factor for adverse outcomes, regardless of the age of the patients.
Asunto(s)
Unidades de Cuidados Intensivos , Insuficiencia Multiorgánica , Humanos , Anciano , Pronóstico , Troponina , Factores de RiesgoRESUMEN
The ever-growing morbidity, disablement, and mortality from coronary heart disease, chronic cardiac failure dictate the necessity of the search for new methods to verify, and evaluate prognosis of the clinical course of these diseases. Currently, myocardial perfusion scintiography is most widely used for the purpose.
Asunto(s)
Angina de Pecho/diagnóstico por imagen , Insuficiencia Cardíaca/diagnóstico por imagen , Anciano , Angina de Pecho/fisiopatología , Enfermedad Crónica , Ejercicio Físico , Femenino , Corazón/diagnóstico por imagen , Insuficiencia Cardíaca/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Miocardio/patología , Perfusión/métodos , Cintigrafía , DescansoRESUMEN
The peculiarities of primary arterial hypertension in persons with opposite types of motivational priorities were studied. The features and prevalence of the disease in two populations were analyzed. Group 1 consisted of 141 subjects whose profession and working conditions required maximum realization of the market-oriented motivational dominant ("socially active persons"); Group 2 consisted of 147 "altruistic" type subjects who lacked the first group's motivational dominant. The study found a higher prevalence of the disease and a lower level of psychological health as part of quality of life in Group 1 (p = 0.018); the disease in this group was more intensive and significant structural and functional left ventricular transformation was typical. The absence of pernicious habits and healthy life-style should not be considered primary factors of a more favorable clinical course of the disease in the "altruistic" group.