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1.
J Paediatr Child Health ; 59(8): 974-978, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-37246761

RESUMEN

AIM: Compared to open pyeloplasty (OP), we hypothesised that laparoscopic pyeloplasty (LP) is associated with early recovery, a shorter length of stay (LOS) and less analgesia requirement. METHODS: Between 2011 and 2016, 146 dismembered pyeloplasty cases were reviewed, of which 113 were in the OP group and 33 were in the LP group. We evaluated both groups regarding operative time, LOS, success rate, complications rate and analgesia requirement. Subgroup analysis was done for patients above the age of 5 years, and within the OP group (dorsal lumbotomy (DL) vs. loin incision (LI)). RESULTS: The success rate was 96% in the open group and 97% in the laparoscopic group. The median operative time was significantly shorter in the open group for the entire cohort (127 vs. 200 min; P < 0.05), and in children older than 5 years (n = 41, 134 vs. 225 min; P < 0.05). Other parameters were similar in both groups. The median LOS was significantly shorter (2 vs. 4 days; P < 0.05), and the median analgesia requirement was less (0.44 vs. 0.64 mg/kg morphine; P < 0.05) in the DL (n = 60) compared to LI (n = 53). CONCLUSION: Both OP and LP dismembered approaches are equally effective in treating pelvi-ureteric junction obstruction. Overall, the LOS, complications rate and analgesia requirement were not significantly different; however, the operative time was significantly longer in LP.


Asunto(s)
Laparoscopía , Obstrucción Ureteral , Niño , Humanos , Preescolar , Pelvis Renal/cirugía , Resultado del Tratamiento , Procedimientos Quirúrgicos Urológicos/efectos adversos , Obstrucción Ureteral/cirugía , Obstrucción Ureteral/etiología , Dolor , Estudios Retrospectivos
2.
World J Surg ; 46(3): 476-485, 2022 03.
Artículo en Inglés | MEDLINE | ID: mdl-34846547

RESUMEN

BACKGROUND: The Global Initiative for Children's Surgery (GICS) group produced the Optimal Resources for Children's Surgery (OReCS) document in 2019, listing standards of children's surgical care by level of healthcare facilities within low resource settings. We have previously created and piloted an audit tool based on the OReCS criteria in a high-income setting. In this study, we aimed to validate its use in identifying gaps in children's surgery provision worldwide. METHODS: Our OReCS audit tool was implemented in 10 hospitals providing children's surgery across eight countries. Collaborators were recruited via the Oxford Paediatrics Linking Our Research with Electives (OxPLORE) international network of medical students and trainees. The audit tool measured a hospital's current capacity for children's surgery. Data were analysed firstly to express the percentage of 'essential' criteria met for each specialty. Secondly, the 'OxPLORE method' was used to allocate each hospital specialty a level based on procedures performed and resources available. A User Evaluation Tool (UET) was developed to obtain feedback on the ease of use of the tool. RESULTS: The percentage of essential criteria met within each category varied widely between hospitals. The level given to hospitals for subspecialties based on OReCS criteria often did not reflect their self-defined level. The UET indicated the audit tool was practicable across multiple settings. CONCLUSIONS: We recommend the use of the OReCS criteria to identify areas for local hospital improvement and inform national children's surgical plans. We have made informed suggestions to increase usability of the OReCS audit tool.


Asunto(s)
Cirugía General , Accesibilidad a los Servicios de Salud , Niño , Estudios Transversales , Humanos
3.
Pediatr Transplant ; 21(4)2017 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-28332273

RESUMEN

We aimed to assess the incidence of HAT over three eras following implementation of microvascular techniques and a customized anticoagulation protocol in a predominantly cadaveric split liver transplant program. We retrospectively reviewed pediatric liver transplants performed between April 1986 and 2016 and analyzed the incidence HAT over three eras. In E1, 1986-2008, each patient received a standard dose of 5 U/kg/h of heparin and coagulation profiles normalized passively. In E2, 2008-2012, microvascular techniques were introduced. In E3, 2012-2016, in addition, a customized anticoagulation protocol was introduced which included replacement of antithrombin 3, protein C and S, and early heparinization. A total of 317 liver transplants were completed during the study period, with a median age of 31.7 months. In E1, 22% of grafts were cadaveric in situ split grafts, while the second and third eras used split grafts in 59.0% and 64.9% of cases, respectively. HAT occurred in 9.5% in the first era, 11.5% (P=.661) in the second, and dropped to 1.8% in the third era (P=.043). A routine anticoagulation protocol has significantly reduced the incidence of HAT post-liver transplantation in children in a predominantly cadaveric in situ split liver transplant program.


Asunto(s)
Anticoagulantes/uso terapéutico , Arteria Hepática , Trasplante de Hígado/métodos , Microcirugia/métodos , Complicaciones Posoperatorias/prevención & control , Trombosis/prevención & control , Procedimientos Quirúrgicos Vasculares/métodos , Niño , Preescolar , Protocolos Clínicos , Terapia Combinada , Quimioterapia Combinada , Femenino , Arteria Hepática/cirugía , Humanos , Incidencia , Lactante , Masculino , Cuidados Posoperatorios/métodos , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Trombosis/epidemiología , Trombosis/etiología , Resultado del Tratamiento
4.
J Pediatr Surg ; 52(3): 395-399, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-27634559

RESUMEN

BACKGROUND: Up to 10% of hypertensive children will have renovascular disease. Where medical therapy fails to control the hypertension, endovascular techniques can improve renal perfusion. The purpose of this study was to assess the efficacy of angioplasty in controlling renovascular hypertension (RVH) in children. METHODS: This is a single-center, retrospective review of patients who underwent angioplasty for RVH between 1992 and 2009. All patients were selected from the Interventional Radiology database. The primary outcome measure was clinical success as reflected by a favorable, sustained response in blood pressure for at least 1year following the angioplasty. RESULTS: Two hundred sixteen patients underwent diagnostic angiography for suspected RVH, of these 28 required 42 angioplasties. Ten (36%) were cured, 9 (32%) were improved and 9 (32%) failed to respond to treatment. Major complications occurred in three patients and minor complications occurred in 18 angioplasties. Fibromuscular dysplasia (FMD) was the most common diagnosis in this series and was associated with a 79% success rate. CONCLUSION: In our exclusively pediatric population angioplasty safely improved blood pressure control in 68% of patients, more than half of which are cured. FMD appeared to have the best clinical outcomes in our series.


Asunto(s)
Angioplastia , Hipertensión Renovascular/terapia , Riñón/irrigación sanguínea , Arteria Renal/diagnóstico por imagen , Adolescente , Angiografía , Presión Sanguínea , Niño , Bases de Datos Factuales , Femenino , Displasia Fibromuscular/complicaciones , Displasia Fibromuscular/terapia , Humanos , Hipertensión Renovascular/diagnóstico por imagen , Hipertensión Renovascular/etiología , Riñón/diagnóstico por imagen , Masculino , Estudios Retrospectivos
5.
J Pediatr Surg ; 50(12): 2137-40, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26388124

RESUMEN

PURPOSE: The purpose of this study was to analyze the general surgical complications in pediatric liver transplant recipients and the safety of delayed primary closure at a single tertiary center. METHODS: A retrospective review of all liver transplant recipients between April 1986 and May 2014 was performed. All general and gastrointestinal complications were recorded and analyzed. The incidence and risk of these complications were compared between children who had a primary versus those who had a delayed closure, with or without the use of Surgisis®, of their abdomen. RESULTS: 242 patients underwent 281 liver transplants. The median age of the children was 31months. Whole (77), reduced size (91), split (96), and living related grafts (17) were used. General surgical complications were observed in 33 cases (11.7%). 135 cases underwent delayed primary closure (DPC) of their abdomen, 35 with Surgisis®. Patients with biliary atresia had a higher rate (4.6%) of bowel perforation (p=0.013). The majority of complications occurred within 3months of transplantation. CONCLUSION: General surgical complications postpediatric liver transplantation were common but usually not life threatening. Delayed primary closure was safe, had no significant long-term issues, and was not associated with higher incidence of wound related complications.


Asunto(s)
Técnicas de Cierre de Herida Abdominal/efectos adversos , Trasplante de Hígado/efectos adversos , Técnicas de Cierre de Herida Abdominal/instrumentación , Adolescente , Atresia Biliar/complicaciones , Atresia Biliar/cirugía , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Estudios Retrospectivos , Resultado del Tratamiento
6.
J Pediatr ; 164(2): 327-31, 2014 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-24252783

RESUMEN

OBJECTIVE: To examine how a mass-gathering event (the Federation Internationale de Football Association World Cup, 2010, South Africa) impacts trauma and mortality in the pediatric (≤ 18 years) population. STUDY DESIGN: We investigated pediatric emergency visits at Cape Town's 3 largest public trauma centers and 3 private hospital groups, as well as deaths investigated by the 3 city mortuaries. We compared the 31 days of World Cup with equivalent periods from 2007-2009, and with the 2 weeks before and after the event. We also looked at the World Cup period in isolation and compared days with and without games in Cape Town. RESULTS: There was significantly decreased pediatric trauma volume during the World Cup, approximately 2/100,000 (37%) fewer injuries per day, compared with 2009 and to both pre- and post-World Cup control periods (P < .001). This decrease occurred within a majority of injury subtypes, but did not change mortality. There were temporal fluctuations in emergency visits corresponding with local match start time, with fewer all-cause emergency visits during the 5 hours surrounding this time (-16.4%, P = .01), followed by a subsequent spike (+26.2%, P = .02). There was an increase in trauma 12 hours following matches (+15.6%, P = .06). CONCLUSIONS: In Cape Town, during the 2010 Federation Internationale de Football Association World Cup, there were fewer emergency department visits for traumatic injury. Furthermore, there were fewer all-cause pediatric emergency department visits during hometown matches. These results will assist in planning for future mass-gathering events.


Asunto(s)
Fútbol/lesiones , Heridas y Lesiones/epidemiología , Heridas y Lesiones/etiología , Adolescente , Niño , Preescolar , Estudios Transversales , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Estudios Prospectivos , Factores de Riesgo , Sudáfrica/epidemiología , Tasa de Supervivencia/tendencias
7.
Urology ; 81(6): 1349-51, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-23622769

RESUMEN

This report describes the use of a biosynthetic graft (Permacol) derived from porcine dermal collagen to reconstruct the abdominal wall of a 2-year-old boy with classic bladder exstrophy. The child had undergone 2 previous failed attempts at closure.


Asunto(s)
Materiales Biocompatibles/uso terapéutico , Extrofia de la Vejiga/cirugía , Colágeno/uso terapéutico , Fístula Cutánea/cirugía , Fístula de la Vejiga Urinaria/cirugía , Extrofia de la Vejiga/complicaciones , Preescolar , Fístula Cutánea/etiología , Humanos , Masculino , Fístula de la Vejiga Urinaria/etiología , Técnicas de Cierre de Heridas
8.
Pediatr Surg Int ; 29(7): 741-4, 2013 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-23411613

RESUMEN

A 2-year-old female presented acutely with peritonitis and small bowel obstruction. An abdominal radiograph demonstrated a radiopaque foreign body. At laparotomy she was found to have bowel perforations with entero-enteric fistulae caused by four magnets. The magnets were removed, and debridement and closure of the perforations performed. We review our case and highlight this problem to other medical practitioners as a potential cause of significant morbidity and mortality in the paediatric population.


Asunto(s)
Cuerpos Extraños/diagnóstico por imagen , Fístula Intestinal/diagnóstico por imagen , Obstrucción Intestinal/diagnóstico por imagen , Perforación Intestinal/diagnóstico por imagen , Imanes/efectos adversos , Juego e Implementos de Juego , Preescolar , Ingestión de Alimentos , Femenino , Estudios de Seguimiento , Cuerpos Extraños/complicaciones , Humanos , Fístula Intestinal/etiología , Fístula Intestinal/cirugía , Obstrucción Intestinal/etiología , Obstrucción Intestinal/cirugía , Perforación Intestinal/etiología , Perforación Intestinal/cirugía , Intestino Delgado/diagnóstico por imagen , Intestino Delgado/cirugía , Radiografía Abdominal/métodos
9.
J Pediatr Surg ; 48(1): 239-42, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23331822

RESUMEN

Here in, we present a case of aggressive Gorham's disease in a 10 year old boy. We document its evolution from a seemingly benign buttock mass to a widely invasive disease that was ultimately fatal. We highlight the challenges in the management of such an aggressive, yet benign process and review the available literature on the subject.


Asunto(s)
Osteólisis Esencial/diagnóstico , Niño , Resultado Fatal , Humanos , Masculino
10.
J Pediatr Surg ; 47(11): 2083-6, 2012 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-23164002

RESUMEN

OBJECTIVE: The objective was to retrospectively review a large series of pediatric patients with genitourinary rhabdomyosarcoma from a developing country. METHODS: A total of 49 children were treated over a 47-year period (1961-2008). Analysis of the clinical presentation, demographics, surgical records, histological results, and oncological management was performed. The patients were analyzed as a whole and also in 2 separate groups (pre- and post-1992). RESULTS: The median age at clinical presentation was 3½ years. The majority (59%) of patients were Intergroup Rhabdomyosarcoma Study group 3, with locally advanced disease at presentation. Twenty (41%) of the 49 patients presented with primary tumors greater than 10 cm in diameter. Sixteen (33%) of the 49 patients had positive regional lymph nodes at presentation. The overall survival of the series was 30 (65%) of 46. The survival for those treated after 1992 in Intergroup Rhabdomyosarcoma Study group 3 was superior (P = .04) to those treated before 1992 (80% vs 56%). CONCLUSION: Children in this large African series of genitourinary rhabdomyosarcoma present with greater locally advanced disease (node positive and bulky disease) when compared with the developed world. Improvements in the last 2 decades in local surgical and oncological care have led to an improvement in survival in children with locally advanced disease.


Asunto(s)
Rabdomiosarcoma , Neoplasias Urogenitales , Adolescente , Niño , Preescolar , Terapia Combinada , Países en Desarrollo , Femenino , Estudios de Seguimiento , Humanos , Lactante , Masculino , Estudios Retrospectivos , Rabdomiosarcoma/diagnóstico , Rabdomiosarcoma/mortalidad , Rabdomiosarcoma/terapia , Sudáfrica , Tasa de Supervivencia , Resultado del Tratamiento , Neoplasias Urogenitales/diagnóstico , Neoplasias Urogenitales/mortalidad , Neoplasias Urogenitales/terapia
11.
J Pediatr Surg ; 47(7): 1463-5, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22813817

RESUMEN

Portal venous gas is one of the classic radiologic features of necrotizing enterocolitis and is an uncommon isolated finding because it is most commonly seen in conjunction with pneumatosis intestinalis. In this case study, we present a preterm neonate with necrotizing enterocolitis who had extensive portal venous gas without obvious pneumatosis intestinalis.


Asunto(s)
Enterocolitis Necrotizante/diagnóstico por imagen , Enfermedades del Prematuro/diagnóstico por imagen , Vena Porta/diagnóstico por imagen , Enterocolitis Necrotizante/fisiopatología , Resultado Fatal , Humanos , Recién Nacido , Recien Nacido Prematuro , Enfermedades del Prematuro/fisiopatología , Masculino , Vena Porta/fisiopatología , Radiografía
12.
J Pediatr Urol ; 8(3): 244-8, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21767991

RESUMEN

Female epispadias is a rare genitourinary anomaly characterized by urinary incontinence and typical appearance of the external genitalia. Traditional surgical approaches have involved a staged genitoplasty and interval bladder neck reconstruction. We describe further experience of a promising single-stage technique using a cystoscopically guided bladder neck plication via a perineal approach with combined genitoplasty.


Asunto(s)
Epispadias/cirugía , Perineo/cirugía , Procedimientos de Cirugía Plástica/métodos , Vejiga Urinaria/cirugía , Procedimientos Quirúrgicos Urológicos/métodos , Niño , Enuresis Diurna/etiología , Enuresis Diurna/fisiopatología , Enuresis Diurna/cirugía , Epispadias/complicaciones , Epispadias/fisiopatología , Femenino , Estudios de Seguimiento , Humanos , Urodinámica
13.
S Afr J Surg ; 49(1): 28-9, 2011 Mar 14.
Artículo en Inglés | MEDLINE | ID: mdl-21933479

RESUMEN

Until recently minimally invastive surgery was not performed in neonates. This was because of their small size and distinct physiological characteristics, neonates were not operated on using minimally invasive surgery until recently. Since the introduction of fine laparoscopic instruments, improvements in the surgical techniques and anaesthetic adjustments for laparoscopy, more complex operations are now being performed in neonates. While certain operations such as laparoscopic pyloromyotomy have become routine in many centres, some others require significant infrastructure and experience. Advantages of minimally invasive surgery seen in older children and adults, such as shortened hospital stay and less pain, also apply to neonates. There is no doubt that minimally invasive surgery for neonates is still in its infancy, and for many neonatal conditions requiring surgery, the benefits of minimally invasive surgery need to be established with well-designed studies.


Asunto(s)
Laparoscopía , Obstrucción Duodenal/cirugía , Enterocolitis Necrotizante/cirugía , Femenino , Humanos , Recién Nacido , Atresia Intestinal , Quistes Ováricos/cirugía
14.
J Urol ; 186(4 Suppl): 1705-9, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21855920

RESUMEN

PURPOSE: We ascertained the incidence and outcome of hydronephrosis related to abdominal or pelvic neoplasms and survival in pediatric patients. MATERIALS AND METHODS: We retrospectively reviewed our institutional oncology database between January 1995 and November 2009. We reviewed the charts of all children with intra-abdominal (nonrenal) and pelvic neoplasms. RESULTS: Of the 366 patients whose charts were reviewed 66 (18%) had hydronephrosis at some point during treatment, including 12 with hydronephrosis that was not caused by the neoplasm and 1 who was lost to followup, leaving 53 with malignant obstruction. Of the remaining patients hydronephrosis resolved in 34 (64%) with treatment for the primary neoplasm alone while in 19 (36%) hydronephrosis persisted after primary oncological treatment. Univariate analysis revealed that patients with persistent hydronephrosis (p = 0.025), those with urological intervention (p = 0.05) and those with high stage disease (p <0.001) had statistically significantly worse overall survival. On Cox multivariate analysis only disease stage remained statistically significant (p = 0.004). CONCLUSIONS: Analysis of this group revealed that pediatric nonrenal abdominal and pelvic tumors are associated with hydronephrosis in about 20% of cases. Approximately 60% of these cases resolved with treatment for the primary tumor alone while 13% required specific urological intervention for urinary tract involvement or compression. Patients with pediatric malignant ureteral obstruction had a 20% 5-year mortality rate. The main predictive factor was primary disease stage.


Asunto(s)
Neoplasias Abdominales/complicaciones , Hidronefrosis/epidemiología , Neoplasias Pélvicas/complicaciones , Neoplasias Abdominales/diagnóstico , Neoplasias Abdominales/mortalidad , Adolescente , Niño , Preescolar , Terapia Combinada , Femenino , Estudios de Seguimiento , Humanos , Hidronefrosis/etiología , Hidronefrosis/cirugía , Incidencia , Lactante , Recién Nacido , Masculino , Ontario/epidemiología , Neoplasias Pélvicas/mortalidad , Neoplasias Pélvicas/terapia , Pronóstico , Estudios Retrospectivos , Análisis de Supervivencia , Tasa de Supervivencia/tendencias , Factores de Tiempo , Obstrucción Ureteral/epidemiología , Obstrucción Ureteral/etiología , Obstrucción Ureteral/cirugía , Procedimientos Quirúrgicos Urológicos
15.
J Pediatr Surg ; 45(8): 1741-7, 2010 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-20713233

RESUMEN

A buried penis secondary to a megaprepuce is defined clinically by a phimosis, failure of the corporal bodies to inhabit a variably deficient penile shaft skin and a basal hemispheric ballooning of the penis during micturition. Anatomically, it describes a condition in which a normal phallus is trapped within normal prepubic connective tissue by the excessive skin of a megaprepuce and a variable abundance of dartos fascia. Many surgical procedures have been described to correct this deformity, suggesting that no single method has a clear advantage. Most of them rely on relatively complex skin flaps or on the abnormal megapreputial tissue for reconstruction of the deficient ventral shaft skin. Herein, the authors describe an alternative technique for ventral skin coverage, the Ventral V-plasty. This surgical procedure allowed for the favorable reconstruction of 10 consecutive children with a buried penis secondary to a megaprepuce. This technique is distinguished by its simplicity and consistent, pleasing cosmetic results.


Asunto(s)
Pene/anomalías , Pene/cirugía , Procedimientos de Cirugía Plástica/métodos , Preescolar , Procedimientos Quirúrgicos Dermatologicos , Prepucio/anomalías , Prepucio/cirugía , Humanos , Lactante , Masculino , Fimosis/cirugía , Colgajos Quirúrgicos , Resultado del Tratamiento , Procedimientos Quirúrgicos Urológicos Masculinos/métodos
17.
J Pediatr Surg ; 42(3): 549-52, 2007 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-17336197

RESUMEN

BACKGROUND: The Bacillus Calmette-Guerin (BCG) vaccine is routinely administered to newborn infants in South Africa. In 2000, a new vaccine, the Danish 1331 strain, was introduced into the Western Cape region. Red Cross Children's Hospital subsequently documented an increase in the number of complications arising from the new vaccine. Since 2004, HIV-positive infants have been treated with highly active antiretroviral therapy (HAART). Coinciding with the roll out of HAART there has been a significant and apparently paradoxical worsening of the complications of the BCG vaccine. METHODS: A retrospective analysis of all HIV-positive infants referred to the surgical department for management of BCG vaccine complications. RESULTS: Fifteen infants were included in this study; they were all HIV-positive. Fourteen infants received HAART. In 10 patients, the implementation of HAART predated the complications of the BCG vaccine by an average of 1.4 months. CONCLUSION: We believe this to be the first description of BCG-associated immune reconstitution inflammatory syndrome. The implications for the operating surgeon are the unique management strategies that should be applied to this disease process and the ongoing research to determine which of these strategies is the most effective.


Asunto(s)
Terapia Antirretroviral Altamente Activa/efectos adversos , Vacuna BCG/efectos adversos , Infecciones por VIH/tratamiento farmacológico , Enfermedades del Sistema Inmune/inducido químicamente , Humanos , Recién Nacido , Estudios Retrospectivos , Tuberculosis/prevención & control
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