RESUMEN

Hyperkalemic periodic paralysis (hyperkalemic PP) is a rare muscle disease that has onset in infancy or early childhood and is manifested by transient episodes of paralysis. In this case we presented a young male adult with attacks of weakness, after commencement of the antiepileptic drug - Carbamazepine. We hypothesize that Carbamazepine, as voltage-gate sodium channel blocker, aggravated the symptoms of hyperkalemic PP, as sodium channelopathies, in this young-male-patient, trough influence on membrane depolarization.

Asunto(s)

Anticonvulsivantes , Enfermedades Musculares , Parálisis Periódica Hiperpotasémica , Adulto , Anticonvulsivantes/efectos adversos , Niño , Preescolar , Humanos , Masculino , Mutación , Bloqueadores de los Canales de Sodio