RESUMEN
Objective: It is well known that celiac disease has a negative influence on patients' health and quality of life. It has a wide range of presentation from symptomless to multiple organ dysfunction but mainly gastrointestinal symptoms. Consequently, it is considered a main cause of mortality, morbidity, and health burden. We aim to evaluate the quality of life affected in gluten-free diet and to identify the serological characteristics of celiac disease patients in the Qassim Region of Saudi Arabia and King Fahad Specialist Hospital. Methods: This is a cross-sectional-based study conducted in King Fahad Specialist Hospital, Saudi Arabia, composed of 58 patients with celiac disease for 9 years between August 2011 and August 2020. Results: Fifty-eight patents were included (79.3% females and 65.5% married), who were divided according to their ages into five groups. Abdominal pain, diarrhea, and/or weight loss were the major patient complaints. A total of 64% of the patients had a +ve (tTG) IgA test at the time of diagnosis, while 17% were -ve. Of the studied patients, 78% reported that they had undergone a duodenal biopsy sampling. No other significant abnormalities were detected between females and males or among the five diagnosed age groups. Conclusion: Patients with celiac disease reported poor health-related quality of life across the board. However, social interaction, emotional role functioning, and emotional well-being were the most important factors.
RESUMEN
Crohn's disease (CD) is a chronic inflammatory disease and is an autoimmune disorder. Due to its remission and relapse cycle, the integrity of the intestinal wall becomes compromised in patients with inflammatory bowel disease. This increases susceptibility to bowel perforation following mechanical injury, especially in patients using immunosuppressive therapy. However, few reports discuss the severity of injury after abdominal trauma in Crohn's patients and how much mild abdominal blunt trauma in such patients can be different in the presentation clinically in correlation with the severity of the intraoperative findings. We report a case of ascending colon perforation secondary to mild abdominal blunt trauma in a patient with CD.