RESUMEN
An adult domestic rabbit showing neurological signs was subjected to euthanasia. At necropsy, macroscopical lesions were absent. Histopathologically, extensive lesions were seen, particularly in the cerebral cortex. Non-suppurative meningitis was present and there was lymphocytic and plasmacytic perivascular cuffing in the neuropil. The cerebral cortex showed extensive segmental neuronal and glial necrosis. Within the necrotic areas, large amphophilic intranuclear inclusion bodies were present in neurons and glial cells. Immunohistochemically, neurons and glial cells in the affected areas were labelled by polyclonal antibodies against both herpes simplex virus-1 (HSV-1) and HSV-2. The agent was classified as HSV-1 by polymerase chain reaction analysis. This is only the second reported natural case of herpes simplex infection in a rabbit.
Asunto(s)
Corteza Cerebral/patología , Encefalitis por Herpes Simple/veterinaria , Herpesvirus Humano 1/aislamiento & purificación , Conejos , Animales , Antígenos Virales/análisis , Cápside/ultraestructura , Núcleo Celular/ultraestructura , Núcleo Celular/virología , Corteza Cerebral/virología , ADN Viral/análisis , Encefalitis por Herpes Simple/patología , Resultado Fatal , Herpesvirus Humano 1/genética , Herpesvirus Humano 1/inmunología , Herpesvirus Humano 1/ultraestructura , Herpesvirus Humano 2/inmunología , Técnicas para Inmunoenzimas/veterinaria , Cuerpos de Inclusión Viral/ultraestructura , Masculino , Meningitis Aséptica/patología , Meningitis Aséptica/veterinaria , Meningitis Aséptica/virología , Microscopía Electrónica/veterinaria , Neuroglía/metabolismo , Neuroglía/patología , Neuronas/metabolismo , Neuronas/patología , Reacción en Cadena de la Polimerasa/veterinariaRESUMEN
Since a new envelope subgroup (J) of the avian leukosis-sarcomatosis-complex was isolated for the first time from broiler breeders in the United Kingdom in 1989 and was characterized and associated with myeloid leukosis (syn. myelocytomatosis) the emergence of this subgroup was reported from all over the world. Thus the first known case of subgroup J avian leukosis in Switzerland in four imported broiler breeder flocks will be described. A total of 53 broiler breeder birds from four flocks showing reduced performance and increased mortality were submitted for postmortem examination. Approximately 20 blood samples from each flock were monitored serologically for antibodies against avian leukosis virus subgroup J (ALV-J). On necropsy myeloid leukosis (ML) was diagnosed in all four flocks. Furthermore the blood samples of three flocks showed significant ELISA-titres for ALV-J.
Asunto(s)
Virus de la Leucosis Aviar/aislamiento & purificación , Leucosis Aviar/virología , Pollos , Animales , Leucosis Aviar/epidemiología , Leucosis Aviar/patología , Virus de la Leucosis Aviar/clasificación , Médula Ósea/patología , Riñón/patología , Suiza/epidemiologíaRESUMEN
30 broiler flocks from two majors Swiss broiler producing companies were examined for lesions relevant to meat inspection between November 1995 and April 1996. 71.8% of condemned carcasses and viscera were assigned to ascites syndrome, bacterial infections and runting. Other diseases and lesions due to injury or processing were rare. Escherichia coli was responsible for the majority of infections. The average condemnation rate (1.0%) corresponded to findings in literature.