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INTRODUCTION: Distal ureteroscopy for stone extraction is a common procedure that is generally performed with spinal or general anesthesia. We retrospectively reviewed all distal ureteroscopy performed for ureteric stone extraction with conscious sedation at our institution over a 10-year period to determine its efficacy and safety. METHODS: A retrospective chart review was performed of all distal ureteroscopy performed for calculus removal from 2004 to 2014. Patient characteristics, analgesic requirement, tolerability, procedure time, stone size and composition, method of stone extraction, success rate, and complications were collected. RESULTS: Between 2004 and 2014, 314 procedures were performed. Mean age was 53.74 years, with 160 males and 154 females. A success rate of 97% and 10 (3.2%) complications were reported. Mean analgesic requirement was 189 µg of fentanyl (range: 50-400) and 2.79 mg of midazolam (range: 0-8). A total of 263 patients (83.7%) tolerated the procedure well, with only seven (2.2%) having poor tolerability. When comparing females to males, females were found to require less fentanyl (p=0.0001) and midazolam (p=0.0001). When calculi >5 mm were compared to those <5 mm, there was no statistically significant difference in success rate, procedure time, analgesic requirement, tolerability, or complications. CONCLUSION: Distal ureteroscopy with conscious sedation is safe and efficacious. To our knowledge, this is the first report demonstrating stones >5 mm can be safely and effectively treated with conscious sedation during this procedure. The context of our findings must be understood within the limitations of our retrospective analysis.
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Renal primitive neuroectodermal tumor is a rare malignancy. These tumours rarely present with caval involvement. We report 2 cases of primitive neuroectodermal tumours (PNETs) with inferior vena cava involvement. The initial presentation and outcomes differed significantly. The diagnosis was confirmed using histologic and pathologic analysis. We present a brief literature review and an outline of typical clinical and pathologic features of renal PNETs.
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Actinomycosis of the urinary bladder is a rare anaerobic bacterial infection caused by Actinomyces isrealii. Initial diagnosis is often difficult and this disease is easily misdiagnosed as a urothelial or urachal tumour. The definitive diagnosis is usually made postoperatively via tissue pathology. We discuss a case of a 54-year-old male with a smoking history and a 2.5-week history of gross hematuria. Ultrasound, computed tomography and cystoscopy revealed a large inflammatory mass adherent to the right, anterior bladder wall, suggesting malignancy. Transurethral resection and histological pathology subsequently confirmed inflammatory urothelium and gram-positive bacteria consistent with actinomyces species.
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PURPOSE: We retrospectively assessed outcomes in a single institution series of percutaneous nephrolithotomy using retrograde nephrostomy access. MATERIALS AND METHODS: We retrospectively evaluated the records of 333 consecutive patients treated between May 2003 and July 2008. Measured variables included patient demographics, retrograde nephrostomy site, postoperative drainage, operative time, stone clearance rate and degree, requirement for secondary procedures, stone composition and complications. RESULTS: A total of 333 patients were included in study, including 162 females and 171 males with a median age of 56 years (range 17 to 87). Median hospital stay was 2 days (range 1 to 13). Antegrade access was required in 14 patients (4%) due to difficult or suboptimal anatomy. A nephrostomy tube was placed in 33 of 329 patients (10%), mainly for postoperative irrigation. Mean operative time was 76 minutes (range 25 to 246). Of the patients 79% achieved complete clearance, 19% had residual fragments 4 mm or less and 2% had significant persistent stones greater than 4 mm. Postoperatively 11 patients (3%) required shock wave lithotripsy. Analysis revealed calcium oxalate in 57% of stones, uric acid in 24%, struvite in 5% (infection stones) and other in 21%. Complications included 4 patients (1%) with significant postoperative hemorrhage, including angioembolization in 2, transfusion of 4 U packed red blood cells in 1 and observation in 1. CONCLUSIONS: The retrograde technique to establish a percutaneous nephrostomy tract for percutaneous nephrolithotomy is safe and effective with stone clearance and complication rates comparable to those of antegrade access.
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Nefrostomía Percutánea/métodos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Nefrostomía Percutánea/efectos adversos , Estudios Retrospectivos , Adulto JovenRESUMEN
Increasing data advocates the wider use of partial nephrectomy for renal tumours amenable to this approach. We describe the initial North American use of a novel parenchymal clamp in an open and a laparoscopic partial nephrectomy. Initial results in 3 patients (2 open, 1 laparoscopic) demonstrate excellent preservation of renal function and good oncologic outcomes. Hilar dissection was avoided in all cases and the estimated blood loss was low. In our small series, we found this device to be a safe and useful adjunct to partial nephrectomy.