RESUMEN
Hypercalcemia in a 4-year-old boy with non-Hodgkin lymphoma treated with pamidronate is presented. The child had relapsed disease with bone metastasis. Hypercalcemia is rare in children, and bisphosphonates are relatively new agents for the treatment of hypercalcemia. Information concerning their use in the treatment of hypercalcemia in childhood is limited. We found that pamidronate is effective and has no significant side effects in a child.
Asunto(s)
Difosfonatos/uso terapéutico , Hipercalcemia/tratamiento farmacológico , Linfoma no Hodgkin/complicaciones , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Calcitonina/uso terapéutico , Preescolar , Glucocorticoides/uso terapéutico , Humanos , Hipercalcemia/etiología , Linfoma no Hodgkin/tratamiento farmacológico , Masculino , Pamidronato , Prednisolona/uso terapéuticoRESUMEN
An 8-year-old boy had nausea and vomiting associated with nystagmus, ataxia, and dysarthria of acute onset. Three years later he had a mass in the anterior mediastinum as a result of Hodgkin disease of mixed cellularity. This association of paraneoplastic cerebellar degeneration with Hodgkin disease has been described in adults.