RESUMEN
This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like cutaneous lesions. The patients began the treatment in 2013 at Hospital Universitário Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio de Janeiro (UFRJ). The first case (mild form) was treated with trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and, then, with half the dose for nine months; the second (moderate form), with itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of the sarcoid-like cutaneous lesions and the differential diagnoses for other granulomatous diseases.
Asunto(s)
Paracoccidioidomicosis/complicaciones , Sarcoidosis/complicaciones , Antifúngicos/uso terapéutico , Enfermedad Crónica , Humanos , Itraconazol/uso terapéutico , Masculino , Persona de Mediana Edad , Paracoccidioidomicosis/tratamiento farmacológico , Paracoccidioidomicosis/patología , Sarcoidosis/patología , Índice de Severidad de la Enfermedad , Combinación Trimetoprim y Sulfametoxazol/uso terapéuticoRESUMEN
ABSTRACT This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like cutaneous lesions. The patients began the treatment in 2013 at Hospital Universitário Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio de Janeiro (UFRJ). The first case (mild form) was treated with trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and, then, with half the dose for nine months; the second (moderate form), with itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of the sarcoid-like cutaneous lesions and the differential diagnoses for other granulomatous diseases.