RESUMEN
BACKGROUND: Ulcerative colitis is a recurrent inflammatory disorder of the colonic mucosa with a growing global prevalence. Diet is known as a key factor related to the risk of developing UC. This study aimed to determine the association between dietary patterns and UC risk. METHODS: In this case-control study, participants' dietary data were recorded using a 168-item Food Frequency Questionnaire, and then the obtained information was classified into 33 food groups. To identify major dietary patterns, a factor analysis method was applied. Multivariable logistic regression was performed to identify the association between identified dietary patterns and UC risk. RESULTS: Data of 81 patients, who suffered from UC, and 163 healthy controls were assessed. Three dietary patterns were identified and named as "western", "traditional", and "healthy" dietary patterns. After the potential confounders were taken into account, the healthy dietary pattern was associated with a reduced odds of UC (OR = 0.22, 95% CI = 0.08-0.57, p < 0.05), whilst the traditional dietary pattern was related to a greater risk of the disease (OR = 4.67, 95% CI = 3.55-23.36, p < 0.05). However, we failed to find any significant relationship between the western dietary pattern and UC risk. CONCLUSION: The present study suggested that adherence to a healthy diet might decrease the risk of developing UC, whereas, following Iranian traditional dietary patterns could enhance the odds of the outcome.
Asunto(s)
Colitis Ulcerosa , Estudios de Casos y Controles , Colitis Ulcerosa/epidemiología , Dieta Saludable , Dieta Occidental/efectos adversos , Humanos , Irán/epidemiologíaRESUMEN
The development of biopolymer-based green packaging films has gained remarkable attention in recent years. In this study, curcumin active films were prepared using different proportions of gelatin (GE) and a soluble fraction of tragacanth gum (SFTG) (1GE:1SFTG and 2GE:1SFTG) by complex coacervation. The various ratios of used biopolymers did not significantly impact the mechanical properties, thickness, and WVP of final films. However, biopolymers' ratio impacted the moisture content, water solubility, swelling ratio, and release rate. Blending curcumin with biopolymers caused a reduction in tensile strength (from 1.74 MPa to 0.62 MPa for film containing 1GE:1SFTG and from 1.77 MPa to 0.17 MPa for film containing 2GE:1SFTG) and proliferation in elongation at break (from 81.48% to 122.00% for film containing 1GE:1SFTG and from 98.87% to 109.58% MPa for film containing 2GE:1SFTG). Moisture content and water solubility of films experienced a decrease after the addition of curcumin. Antioxidant activity of curcumin-loaded films was almost five times higher than neat film samples. Furthermore, the interreaction between the carboxylic group of SFTG and amide I of GE formed an amide linkage and was proven by FTIR analysis. TGA showed a drop in the thermal stability of film samples compared to the main ingredients. In general, the complex coacervate of SFTG and GE has the advantage of developing eco-friendly and low-cost packaging film in the food industry, especially for the protection of fatty foods.