RESUMEN

Idiopathic nephrotic syndrome (INS) in black African children differs from that of children in temperate areas. The main differences are the high rate of corticosteroid non-responders and the low rate of minimal change glomerulopathy in black African children, possibly related to a racial factor. The identification of a high corticosensibility in certain African regions (Togo and Ghana) can lead to the identification of an ethnic factor. Further genetic studies should be carried out in order to provide a better approach to INS in Africa.

Asunto(s)

Población Negra/genética , Síndrome Nefrótico/genética , Corticoesteroides/administración & dosificación , África , Niño , Resistencia a Medicamentos , Ghana , Humanos , Nefrosis Lipoidea/diagnóstico , Nefrosis Lipoidea/tratamiento farmacológico , Nefrosis Lipoidea/genética , Síndrome Nefrótico/diagnóstico , Síndrome Nefrótico/tratamiento farmacológico , Togo