RESUMEN

We report a case of isoniazid induced convulsions in 35 years old male alcoholic and smoker patient receiving intensive phase therapy for pulmonary tuberculosis. A case was confirmed by accidental positive de-challenge and rechallenge as well as ruled out other conditions. Use of isoniazid in alcoholic and smoker patient required a caution for prevention of neurological adverse reactions. Pyridoxine should always be prescribed to such patients for the prevention of such adverse reaction.

Asunto(s)

Alcoholismo/complicaciones , Antituberculosos/efectos adversos , Isoniazida/efectos adversos , Convulsiones/inducido químicamente , Fumar/efectos adversos , Tuberculosis Pulmonar/tratamiento farmacológico , Adulto , Anticonvulsivantes/uso terapéutico , Humanos , Masculino , Piridoxina/uso terapéutico , Factores de Riesgo , Convulsiones/diagnóstico , Convulsiones/tratamiento farmacológico , Resultado del Tratamiento , Tuberculosis Pulmonar/diagnóstico , Tuberculosis Pulmonar/microbiología , Complejo Vitamínico B/uso terapéutico