RESUMEN
In this work, quercetin (Que) molecular imprinted polymer (MIP) material decorated on magnetic graphene oxide (MGO) with high performance was prepared for the first time using a surface-imprinting technique. Magnetic graphene oxide was synthesized using the solvothermal route. Methacrylic acid (MAA) was used as functional monomer, ethylene glycol dimethyl acrylate (EGDMA) as cross-linker; Que. was used as template, for the decoration with MIP. The prepared nanocomposite was examined by different characterization methods including fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM). The adsorption performance was investigated. MGO-MIP was found to have high loading (369â¯mgâ¯g-1) and selective capacity making the nanomaterial more performant than previous similar reported nanomaterials. The determination of Que. was carried out by mean of magnetic solid phase extraction method coupled with high-performance liquid chromatography (HPLC) and the extraction conditions studies were also performed out. Under the optimized conditions, MGO-MIP showed great performance for the extraction, separation and determination of Que. in green tea and serum samples, compared to the flavonoid analogs luteolin (Lut) and rutin (Rut) in the same matrix samples.