RESUMEN
The authors describe in a systemic order the potentialities of the use of nuclear medicine methods in immunology. Two fields of their application were singled out: experimental and clinical immunology, each one including in vivo and in vitro methods. The authors cited examples of their use, emphasizing the importance and prospects of radioimmunoassays for determination of the level of hormones in patients with various immunological pathology.
Asunto(s)
Sistema Inmunológico/diagnóstico por imagen , Humanos , Técnicas In Vitro , CintigrafíaRESUMEN
The paper is concerned with the results of radioimmunoassay of the CEA level in the blood serum of 235 patients with breast cancer, 48 patients with fibrous-cystic mastopathies and 51 healthy women. In 100 patients with generalized breast cancer repeated examination of the CEA level was done during drug treatment. The authors showed a possibility to use in practice the results of radioimmunoassay of CEA in patients with breast cancer in early stages as a prognostic test as well as an additional criterion in the evaluation of drug therapeutic efficacy in patients with generalized breast cancer.
Asunto(s)
Neoplasias de la Mama/sangre , Antígeno Carcinoembrionario/análisis , Femenino , Enfermedad Fibroquística de la Mama/sangre , Humanos , Neoplasias Hormono-Dependientes/sangre , Pronóstico , RadioinmunoensayoRESUMEN
Levels of thyroid hormones and thyrotropin in 58 cases of adenoma and 86 cases of cancer of the thyroid gland were assayed radioimmunologically. Secretory function of the thyroid gland was inhibited in cancer patients and increased in adenoma group. Due to feedback, peripheral blood--thyrotropin levels were lowered in adenoma patients and raised in the cancer group. The hormonal disturbances were not identical in males and females; they were more pronounced in patients with disseminated tumor aged 46-55. The latter finding points to a decline in thyroid function with aging.