RESUMEN
The authors report a case-study on 104 children admitted for many reasons to the I Department of Pediatrics of the A. Meyer Hospital in the period 1979-81. During their hospitalization, otitis media was diagnosed in all these cases. The children later underwent two check-ups including otorhinolaryngologic and tympanometric tests and in some cases an audiometric examination. A correlation between otitis media and enlarged adenoids was noticed and the results of the present case-study are compared with other international publications, following the short bibliography.
Asunto(s)
Otitis Media/diagnóstico , Adenoidectomía , Tonsila Faríngea , Factores de Edad , Niño , Preescolar , Femenino , Estudios de Seguimiento , Pérdida Auditiva Conductiva/etiología , Humanos , Lactante , Recién Nacido , Enfermedades Linfáticas/complicaciones , Masculino , Otitis Media/complicacionesRESUMEN
The AA describe a case of Larva Migrans Visceral syndrome in a two year-old boy in systemic form with negative outcome. The autoptic examination showed a "granulomatous hepatitis with marked component of eosinophil cells'. The presence of "eosinophil granuloma' in liver has led to the diagnosis of Visceral Larva Migrans Syndrome; other possible causes of Ipereosinophilous Syndrome have been excluded on the basis of anamnestic, clinic and laboratory data. The discovery in the medical history of frequent contacts with a dog which was affected by a serious toxocara canis infections, has led to the diagnosis of Larva Migrans Syndrome from Toxocara canis.
Asunto(s)
Larva Migrans Visceral/etiología , Preescolar , Diagnóstico Diferencial , Humanos , Larva Migrans Visceral/diagnóstico , Masculino , Síndrome de Reye/diagnósticoAsunto(s)
Distrofias Musculares/diagnóstico , Adolescente , Biopsia , Niño , Preescolar , Creatina Quinasa/sangre , Electrocardiografía , Electromiografía , Femenino , Fructosa-Bifosfato Aldolasa/sangre , Humanos , Hidroxibutirato Deshidrogenasa/sangre , Lactante , Isoenzimas , L-Lactato Deshidrogenasa/sangre , Estudios Longitudinales , Masculino , Músculos/patología , Distrofias Musculares/enzimología , Distrofias Musculares/patología , Pronóstico , Espirometría , Transaminasas/sangreRESUMEN
An investigation was carried out to establish the incidence of X-linked progressive muscular dystrophies in Tuscany from 1966 to 1974. 52 cases were identified, the incidence being 23,95 X 10(-5) with reference to live-born males. The frequency of new mutations calculated according to Haldane's method was 7,97 X 10(-6). These data practically correspond to those reported by other AA. in Italy and abroad. There was also a remarkable variability in the incidence among individual districts with values ranging from 7,60 X 10(-5) to 41,91 X 10(-5). It was noticed that the number of new cases tended to decrease in the last few years.
Asunto(s)
Distrofias Musculares/genética , Femenino , Humanos , Italia , Distrofias Musculares/epidemiología , Mutación , Cromosoma XRESUMEN
Some immunological parameters have been examined in eleven children with juvenile rheumatoid arthritis. A quantitative and functional defect in T lymphocytes has been observed associated with defective chemotaxis of neutrophils. High levels of circulating immune-complexes were detected in sera of 5 out 11 patients. 1 patient showed high levels of antinuclear antibodies and positivity for the rheumatoid factor. Immunological pathogenesis of juvenile rheumatoid arthritis is discussed.
Asunto(s)
Artritis Juvenil/inmunología , Quimiotaxis de Leucocito , Síndromes de Inmunodeficiencia , Adolescente , Niño , Preescolar , Femenino , Humanos , Inmunidad Celular , Activación de Linfocitos , Masculino , Neutrófilos , Formación de Roseta , Linfocitos T/inmunologíaAsunto(s)
Distrofias Musculares/diagnóstico , Xerorradiografía , Adolescente , Niño , Preescolar , Pruebas Enzimáticas Clínicas , Técnicas de Laboratorio Clínico , Electromiografía , Femenino , Humanos , Masculino , Distrofias Musculares/diagnóstico por imagen , Xerorradiografía/instrumentación , Xerorradiografía/métodosRESUMEN
Gastrocnemius muscle fragments of children affected by clinically diagnosed progressive muscular dystrophy of Duchenne have been studied. At the light microscope, in the semi-thin sections, the more evident changes are represented by a wide diameter range of the fibers and fatty infiltration. Some fibers show numerous nuclei in their central part, a sarcoplasmic degeneration of vacuolar type and an irregular and tortuous course of the myofibrils. Moreover, the ultrastructural findings have shown characteristic changes in myofilaments and Z bands represented by: streaming of the Z bands, collection of the triads and concentric laminated bodies. These observations have pointed out a certain gradualness of the alterations, starting from focal changes of Z band to the complete disarrangement of myofilaments.