RESUMEN
AIMS: To compare patients with acute necrotizing pancreatitis without any additional complications during their hospital stay (Group A) versus patients with Acute Necrotizing Pancreatitis with additional complications during their hospital stay (Group B). METHODS: Data obtained from a pre-existing base from hospitalized patients with diagnosis of acute necrotizing pancreatitis in the specialized unit of "Unidad de Pancreatitis Aguda Grave del Hospital Nacional Edgardo Rebagliati Martins" between 2000 and 2010. Data included patients with diagnosis of acute necrotizing pancreatitis, of ages 18 and over. RESULTS: Data from 215 patients with acute necrotizing pancreatitis was included. Patients from Group A represented 32% (68) and from Group B 68% (147). Group A had a average of 39 hospitalized days and Group B had an average of 56 days (p=0.01). From Group A 22% had more than 50% of necrosis while 43% of Group B had this extension of necrosis (p <0.05, OR 3.4, IC (1.12-10)). Of the 14 deaths of the population, all part of Group B, 12 of them had more than 50% of necrosis. CONCLUSIONS: Not every patient classified as severe acute pancreatitis, based on the presence of necrosis, behave likewise. It is an extended necrosis, described as more than 50% of pancreatic necrosis, and not the presence itself which will determine additional complications during the course of disease and a greater mortality.
Asunto(s)
Pancreatitis Aguda Necrotizante/diagnóstico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Necrosis , Páncreas/patología , Pancreatitis Aguda Necrotizante/complicaciones , Pancreatitis Aguda Necrotizante/mortalidad , Pancreatitis Aguda Necrotizante/patología , Pronóstico , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Adulto JovenRESUMEN
OBJETIVOS: Comparar a pacientes con pancreatitis aguda con necrosis que no presentan complicaciones adicionales durante su hospitalización (Grupo A) versus aquellos pacientes con pancreatitis aguda con necrosis que presenten complicaciones adicionales durante su hospitalización (Grupo B). MÉTODOS: Se realizó el análisis sobre una base de datos preexistente de registros de pacientes hospitalizados con diagnóstico de pancreatitis aguda con necrosis de la Unidad de Pancreatitis Aguda Grave del Hospital Nacional Edgardo Rebagliati Martins entre 2000 y 2010. Se utilizaron los registros de todos los pacientes criterios diagnósticos de pancreatitis aguda severa con presencia de necrosis mayores de 18 años. RESULTADOS: Se incluyeron 215 registros de pacientes con PA con necrosis. Los pacientes del Grupo A representaron un 32% (68) y los del Grupo B el 68%(147). Grupo A tuvo un promedio de 39 días de hospitalización y el Grupo B tuvo un promedio de 56 días (p = 0.01). Del Grupo A 22% tuvieron más de 50% de necrosis mientras 43% del Grupo B tuvieron esta extensión de necrosis (p <0.05, OR 3.4, IC (1.12-10)). De los 14 casos fallecidos de toda la población, encontrándose todos ellos en el Grupo B, 12 de ellos tuvieron más de 50% de necrosis. CONCLUSIONES: No todos los casos clasificados como pancreatitis aguda severa, basados en la presencia de necrosis pancreática, se comportan de manera uniforme. Es la extensión de la necrosis pancreática (mayor a 50%) y no la sola presencia de la misma, la que determinaría una evolución con complicaciones adicionales y mayor mortalidad.
AIMS: To compare patients with acute necrotizing pancreatitis without any additional complications during their hospital stay (Group A) versus patients with Acute Necrotizing Pancreatitis with additional complications during their hospital stay (Group B) METHODS: Data obtained from a pre-existing base from hospitalized patients with diagnosis of acute necrotizing pancreatitis in the specialized unit of "Unidad de Pancreatitis Aguda Grave del Hospital Nacional Edgardo Rebagliati Martins" between 2000 and 2010. Data included patients with diagnosis of acute necrotizing pancreatitis, of ages 18 and over. RESULTS: Data from 215 patients with acute necrotizing pancreatitis was included. Patients from Group A represented 32% (68) and from Group B 68% (147). Group A had a average of 39 hospitalized days and Group B had an average of 56 days (p=0.01). From Group A 22% had more than 50% of necrosis while 43% of Group B had this extension of necrosis (p <0.05, OR 3.4, IC (1.12-10)). Of the 14 deaths of the population, all part of Group B, 12 of them had more than 50% of necrosis. CONCLUSIONS: Not every patient classified as severe acute pancreatitis, based on the presence of necrosis, behave likewise. It is an extended necrosis, described as more than 50% of pancreatic necrosis, and not the presence itself which will determine additional complications during the course of disease and a greater mortality.