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Myxozoa is a class of the Phylum Cnidaria made up of endoparasites from aquatic habitats. The genus Ceratomyxa preferentially infects marine fish, with the gallbladder being the main site parasitized. This study aimed to describe a new species of Ceratomyxa found in this organ in Boulengerella cuvieri using morphological, morphometric characterization and phylogenetic analysis of 18S rDNA gene sequences. Specimens of B. cuvieri were collected, anesthetized, desensitized and biometric measurements were performed. The organs were analyzed under a stereomicroscope and fragments of internal organs were extracted for light microscopy analysis, preserved in 80% ethanol for 18S rDNA gene analysis and fixed in Davidson solution for histological processing. Free spores of Ceratomyxa were observed in the gallbladder, in plasmodia with wave-like movements, with the following dimensions: spore width (24.5 ± 0.4) µm, spore length (5.2 ± 0.3) µm, polar capsule width (1.8 ± 0.2) µm, polar capsule length (2.1 ± 0.3) µm, number of polar tubule turns (4-5) and 100% prevalence. Phylogenetic analysis confirmed that Ceratomyxa matosi n. sp. is a new species, grouped with other freshwater Ceratomyxa species from the Amazon, representing the second description of species of this genus in the state of Amapá.

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ABSTRACT The objective of this case report was to share the successful management of severe endophthalmitis, aiming at ocular integrity and visual acuity. A 73-year-old man presented with visual acuity of 20/30 in the right eye and 20/200 in the left eye. On the 21st day postoperatively after phacoemulsification in the left eye, he developed symptoms of endophthalmitis, including ocular discomfort, blurred vision, and whitish discharge. Despite negative cultures, his condition worsened, resulting in corneal perforation on the 31st day. Conjunctival flap and penetrating keratoplasty were performed. Currently, the patient maintains a visual acuity of 20/40 in the left eye, with a healthy graft and no signs of failure. Despite the complications, careful follow-up and timely interventions successfully preserved his vision. The use of conjunctival flap during the inflammatory phase was crucial to maintaining ocular integrity. This underscores the importance of different approaches in complex ocular complications, including alternative strategies for ocular protection during active inflammation.

RESUMO O objetivo deste relato de caso foi compartilhar o manejo bem-sucedido de uma grave endoftalmite, visando à integridade ocular e à acuidade visual. Um homem de 73 anos apresentou acuidade visual de 20/30 no olho direito e 20/200 no olho esquerdo. No 21° dia pós-operatório de facoemulsificação em olho esquerdo, ele desenvolveu sintomas de endoftalmite, incluindo desconforto ocular, visão embaçada e secreção esbranquiçada. Apesar de culturas negativas, sua condição piorou, resultando em perfuração corneal no 31° dia. A cobertura conjuntival e a ceratoplastia penetrante foram realizadas. Atualmente, o paciente mantém acuidade visual de 20/40 no olho esquerdo, com enxerto saudável e sem sinais de falha. Apesar das complicações, o acompanhamento cuidadoso e as intervenções oportunas preservaram a visão com sucesso. O uso de cobertura conjuntival durante a fase inflamatória foi crucial para manter a integridade ocular. Isso destaca a importância de diferentes abordagens em complicações oculares complexas, incluindo estratégias alternativas para proteção ocular durante a inflamação ativa.

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Abstract Objective To evaluate otolith function by comparing the findings of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential and the ocular Vestibular Evoked Myogenic Potential tests in patients in the inter-crisis period of unilateral definite Meniere's disease. Methods The sample consisted of an experimental group (n = 22; 10 men and 12 women, mean age 47.32 ± 12.82 years) with definite unilateral Meniere's disease and a control group (n = 14; 5 men and 9 women, with a mean age of 41.64 ± 13.45 years). They all underwent vestibular evaluation by means of Subjective Visual Vertical with the bucket method and, cervical and ocular Vestibular Evoked Myogenic Potential tests. The data were collected and subjected to statistical analysis. Results The results of the comparison of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential, the ocular Vestibular Evoked Myogenic Potential and, the association of cervical Vestibular Evoked Myogenic Potential with the ocular Vestibular Evoked Myogenic Potential showed no significant difference, indicating concordance among the tests. Conclusion The identified abnormalities and the concordance between the combined proportion of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential and the ocular Vestibular Evoked Myogenic Potential findings indicate that the association of these three tests contributes to the identification of sustained and transient otolith dysfunction in the inter-crisis of unilateral definite Meniere's disease. Level of evidence 2.

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PURPOSE: To evaluate the chondrotoxic effects of intra-articular use of TXA 20 mg/kg and/or 0.35% PVPI on knee joint cartilage in an experimental model of rabbits. METHODS: Forty-four male New Zealand adult rabbits were randomly assigned to four groups (control, tranexamic acid (TXA), povidone-iodine (PVPI), and PVPI + TXA). The knee joint cartilage was accessed through an arthrotomy and exposed to physiological saline SF 0.9% (control group), TXA, PVPI, and PVPI followed by TXA. Sixty days after surgical procedure, the animals were sacrificed and osteochondral specimens of the distal femur were obtained. Histological sections of cartilage from this area were stained with hematoxylin/eosin and toluidine blue. The following cartilage parameters were evaluated by the Mankin histological/histochemical grading system: structure, cellularity, glycosaminoglycan content in the extracellular matrix, and integrity of the tidemark. RESULTS: The isolated use of PVPI causes statistically significant changes in cartilage cellularity (p-value = 0.005) and decrease glycosaminoglycan content (p = 0.001), whereas the isolated use of TXA decreased significantly the glycosaminoglycan content (p = 0.031). The sequential use of PVPI + TXA causes more pronounced alterations in the structure (p = 0.039) and cellularity (p = 0.002) and decreased content of glycosaminoglycans (p < 0.001) all with statistical significance. CONCLUSION: Data suggest that intra-articular use of tranexamic acid 20 mg/kg and intraoperative lavage with 0.35% povidone-iodine solution for three min are toxic to the articular cartilage of the knee in an experimental in vivo study in rabbits.

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Background People affected by Human Immunodeficiency Virus (HIV), are burdened by a higher risk of developing malignancies including non-melanoma skin cancer (NMSC) and melanoma skin cancer. Objective To evaluate the association of HIV with melanoma and NMSC at a University Hospital. Methods This is a cross-sectional retrospective study of HIV-infected and a matched comparison group, analyzing the associations between skin cancer and HIV infection. Results Compared to the HIV-uninfected, HIV-infected had 80% association with skin cancer (CI 95%: 1.3-2.4, P = 0.001) The risk was 45-fold higher by patients" age (CI 95%: 3.3-15.9: P = 0.001). When adjusted for patient age, sex and race, the risk was 6.4 fold ligher of having cancer if compared to the others (CI 95%: 49-84, P = 0.001). Melanoma was not found in HIV-infected. Conclusion With this study, we have demonstrated that HIV-infected patients have an increased risk of BCC and SCC. Preventive dermatologic management is pivotal in the care of immunosuppressed patients. These patients must undergo the dermatological examination annually and should receive extensive counseling regarding sun avoidance, use of sunscreens,and sun-protective clothing.

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OBJECTIVE: To evaluate otolith function by comparing the findings of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential and the ocular Vestibular Evoked Myogenic Potential tests in patients in the inter-crisis period of unilateral definite Meniere's disease. METHODS: The sample consisted of an experimental group (n=22; 10 men and 12 women, mean age 47.32±12.82 years) with definite unilateral Meniere's disease and a control group (n=14; 5 men and 9 women, with a mean age of 41.64±13.45 years). They all underwent vestibular evaluation by means of Subjective Visual Vertical with the bucket method and, cervical and ocular Vestibular Evoked Myogenic Potential tests. The data were collected and subjected to statistical analysis. RESULTS: The results of the comparison of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential, the ocular Vestibular Evoked Myogenic Potential and, the association of cervical Vestibular Evoked Myogenic Potential with the ocular Vestibular Evoked Myogenic Potential showed no significant difference, indicating concordance among the tests. CONCLUSION: The identified abnormalities and the concordance between the combined proportion of the Subjective Visual Vertical, the cervical Vestibular Evoked Myogenic Potential and the ocular Vestibular Evoked Myogenic Potential findings indicate that the association of these three tests contributes to the identification of sustained and transient otolith dysfunction in the inter-crisis of unilateral definite Meniere's disease.

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RESUMO Objetivo Avaliar o controle postural na doença de Menière. Métodos 34 pacientes com doença de Menière definida (grupo experimental) e 34 indivíduos hígidos (grupo controle), homogêneos quanto à idade e ao gênero, foram submetidos à posturografia do Tetrax Interactive Balance System (Tetrax IBS TM) em oito condições sensoriais. Índice de estabilidade, índice de distribuição de peso, índice de sincronização da oscilação postural direita/esquerda e dedos/calcanhar, frequência de oscilação postural e índice de risco de queda foram analisados. Resultados O índice de estabilidade foi maior no grupo experimental, com diferença significativa entre os grupos, em todas as condições sensoriais testadas. O risco de queda foi maior no grupo experimental do que no grupo controle. A oscilação postural foi maior no grupo experimental em todas as faixas de frequência, com diferença significativa em algumas delas. Não houve diferença significativa entre os grupos nos índices de distribuição de peso e de sincronização, nas oito condições sensoriais avaliadas. Conclusão Pacientes com doença de Menière apresentam comprometimento do controle postural, caracterizado por alterações do índice de estabilidade, em frequências de oscilação postural e no índice de risco de queda.

ABSTRACT Purpose To evaluate postural control in Menière's disease. Methods 34 patients with Menière's disease (experimental group) and 34 healthy individuals (control group) were submitted to Tetrax Interactive Balance System posturography under eight sensory conditions. Stability, weight distribution, synchronization, risk of falling and postural oscillation frequency were analyzed. Results Stability index was higher in the experimental group with significant difference between the groups in all sensory conditions. Risk of falling was higher in the experimental group than in the control. Postural oscillation was higher in the experimental group in all frequency ranges, with significant difference in some of them. There was no significant difference between the groups in the weight distribution and synchronization indexes. Conclusion In this study, Menière's disease patients presented impaired postural control, characterized by postural instability and oscillation and risk of falling.

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O consumo de bebidas alcoólicas, principalmente em jovens, acarreta uma série de efeitos negativos no sistema cardiovascular. Tal uso exacerbado e precoce pode predispor à calcificações coronarianas, aumento na pressão arterial, arritmias cardíacas e insuficiências coronarianas à longo prazo. Em contrapartida, a prática de atividades físicas é uma grande aliada na saúde cardiovascular. Assim, objetiva-se com o presente estudo associar o consumo de bebidas alcoólicas e a prática de atividade física com fatores de risco para doenças cardiovasculares em estudantes universitários. É um estudo observacional transversal. Foram coletados dados de consumo de bebidas alcoólicas (questionário AUDIT), nível de atividade física (IPAQ), índice de massa corporal (IMC), circunferência de cintura (CC), relação cintura quadril (RCQ), pressão arterial sistêmica e histórico de tabagismo. A comparação entre os grupos realizada pelo teste t-Student ou Mann-Whitney. A correlação entre as variáveis pelo Coeficiente de Spearman. Dessa forma, os resultados encontrados foram que os estudantes universitários que consumiam bebida alcóolica e que tiveram risco de dependência (n=40) tiveram maior IMC (Δ=+1,18kg/m2, p=0,049), CC (Δ=+5,77cm, p=0,005) e RCQ (Δ=+0,003, p=0,027). O score da dieta (Δ=+6,39, p=0,056) do grupo ativo foi maior em relação ao sedentário. Houve correlação direta do score do questionário AUDIT com tabagismo (p<0,001), IMC (p=0,010), CC (p=0,005), RCQ (0,045) e atividade física vigorosa (p=0,027) e, desta com tabagismo (p=0,021). Com o estudo, foi perceptível que há alto consumo de bebidas alcoólicas entre os estudantes universitários, mas, baixo o risco de dependência ao álcool. Os estudantes que são etilistas e com risco de dependência tem maiores valores para parâmetros de obesidade incluindo a RCQ que está diretamente relacionada com evento cardiovascular.

The consumption of alcoholic beverages, especially among young people, has a series of negative effects on the cardiovascular system. Such exacerbated and early use may predispose to coronary calcification, increased blood pressure, cardiac arrhythmias, and long-term coronary insufficiency. On the other hand, the practice of physical activities is a great ally in cardiovascular health. Thus, this study aims to associate the consumption of alcoholic beverages and the practice of physical activity with risk factors for cardiovascular diseases in college students. This is a cross-sectional observational study. We collected data on alcohol consumption (AUDIT questionnaire), physical activity level (IPAQ), body mass index (BMI), waist circumference (WC), waist- to-hip ratio (WHR), systemic blood pressure, and smoking history. The comparison between groups was done by the t-Student or Mann-Whitney test. The correlation between variables was done by Spearman's Coefficient. Thus, the results found were that college students who consumed alcoholic beverages and had a risk of addiction (n=40) had higher BMI (Δ= +1.18kg/m2, p=0.049), WC (Δ=+5.77cm, p=0.005) and WHR (Δ=+0.003, p=0.027). The diet score (Δ=+6.39, p=0.056) of the active group was higher compared to the sedentary group. There was direct correlation of AUDIT questionnaire score with smoking (p<0.001), BMI (p=0.010), WC (p=0.005), WHR (0.045) and vigorous physical activity (p=0.027) and, of this with smoking (p=0.021). With the study, it was noticeable that there is high alcohol consumption among college students, but, low risk of alcohol dependence. Students who are alcohol drinkers and at risk of addiction have higher values for obesity parameters including WHR which is directly related to cardiovascular event. KEYWORDS: Alcohol Consumption in College; Physical Exercise; Heart Disease; Risk Factors; Students.

El consumo de bebidas alcohólicas, especialmente entre los jóvenes, tiene una serie de efectos negativos sobre el sistema cardiovascular. Este consumo exacerbado y precoz puede predisponer a la calcificación coronaria, aumento de la presión arterial, arritmias cardiacas e insuficiencia coronaria a largo plazo. Por otro lado, la práctica de actividades físicas es un gran aliado en la salud cardiovascular. Así, este estudio pretende asociar el consumo de bebidas alcohólicas y la práctica de actividad física con factores de riesgo de enfermedades cardiovasculares en estudiantes universitarios. Se trata de un estudio observacional transversal. Se recogieron datos sobre el consumo de alcohol (cuestionario AUDIT), el nivel de actividad física (IPAQ), el índice de masa corporal (IMC), el perímetro de cintura (CC), la relación cintura-cadera (RCC), la presión arterial sistémica y los antecedentes de tabaquismo. La comparación entre los grupos se realizó mediante la prueba t-Student o Mann-Whitney. La correlación entre las variables por el Coeficiente de Spearman. Así, los resultados encontrados fueron que los universitarios que consumían bebidas alcohólicas y tenían riesgo de dependencia (n=40) presentaban mayor IMC (Δ= +1,18kg/m2, p=0,049), CC (Δ=+5,77cm, p=0,005) y RH (Δ=+0,003, p=0,027). La puntuación de la dieta (Δ=+6,39, p=0,056) del grupo activo fue mayor en comparación con el grupo sedentario. Hubo correlación directa de la puntuación del cuestionario AUDIT con el tabaquismo (p<0,001), el IMC (p=0,010), la CC (p=0,005), el RH (0,045) y la actividad física vigorosa (p=0,027) y, de ésta, con el tabaquismo (p=0,021). Con el estudio, se notó que hay alto consumo de bebidas alcohólicas entre los universitarios, pero, bajo riesgo de dependencia del alcohol. Los estudiantes bebedores de alcohol y con riesgo de dependencia presentan valores más elevados en los parámetros de obesidad, incluyendo el WHR que está directamente relacionado con el evento cardiovascular.

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Dental trauma is a public health problem because of its high prevalence rates and treatment costs and for affecting mainly younger individuals. Aim: This cross-sectional study aimed to investigate the variables associated with dental trauma and its influence on oral health-related quality of life among 7th-grade students of public elementary schools. Methods: The data was collected with semi-structured and self-administered questionnaires and an intraoral clinical examination (n = 204). The variables collected regarded dental trauma, lip coverage, overjet, oral health-related quality of life (Child Perceptions Questionnaire - CPQ11-14 ISF: 8), and sociodemographic profile. Association tests and the Mann-Whitney test were performed at a 5% significance level. Results: Dental trauma occurred in 12.3% of students, 94.6% had adequate lip coverage, and the mean overjet was 2.7 mm (±2.0). Sex was the only variable with a statistically significant association with dental trauma (p = 0.021). There was no statistically significant difference in the CPQ11-14 ISF: 8 score between students with and without dental trauma (p = 0.136). Conclusions: Dental trauma was significantly associated with sex and did not impact the oral health-related quality of life of the students

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INTRODUCTION: The varicella vaccine was first introduced into the Brazilian immunization schedule in September 2013 as a single dose for children aged 15 months. In 2018, a second dose was recommended for individuals between 4 and 6 years old. This study aims to assess the impact of routine varicella vaccination on the number and profile of hospitalized varicella patients during the single dose period, as well as in the first two years after the adoption of the second dose. METHODS: An observational retrospective study was conducted in an infectious disease pediatric hospital, in Minas Gerais, Brazil. Clinical as well as epidemiological data from patients hospitalized due to varicella between 2010 and 2019 were collected. Patients were split into groups based on the vaccine introduction: pre-vaccine period, single dose and two-dose period. They were compared by age, sex, reason for admission, illness-related complications and clinical outcome. RESULTS: There were 1193 admissions due to varicella during the studied period. When compared with the pre-vaccine period, the number of hospitalizations decreased in 61.5% during the single-dose regime, reaching 95.2% in the two-dose period. Hospitalization rates decreased in all age groups, including non-vaccinated individuals such as those younger than 12 months (92.1%). As for reasons of admission, secondary bacterial skin infections were perceived to be the most common cause (>70%). A reduction was also seen in admission of immunocompromised or HIV positive patients (84.8%). CONCLUSION: The collected data shows a significant impact in the number of hospital admissions due to varicella after six years of the implementation of the vaccine, positively affecting both vaccinated and non-vaccinated individuals. Further reduction was seen after the second dose was initiated, but its true impact will only be understood fully after a longer period of continuous vaccination.

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INTRODUCTION: Total knee arthroplasty is used to treat end-stage knee osteoarthritis with great results. Tourniquet use has become popular over the years because of its various benefits, but the literature regarding functional outcomes, pain and rehabilitation and comparison between tourniquet use and improvement cement penetration and overall improve fixation is limited. The authors proposed a hypothesis that cementation quality, and clinical outcomes can be influenced by tourniquet technique. METHODS: Fifty patients were allocated randomly in two groups: (1) tourniquet was inflated throughout all the procedure and (2) only during skin incision and cementation. Radiolucent lines were analyzed by two and independent examiners, using the The Knee Society Roentgenographic Evaluation and Scoring System. The functional scores used were the Oxford knee score and improvement in visual pain scale (VAS). RESULTS: After a mean follow-up period of 2.4 ± 0.2 years, no difference was observed regarding partial use of tourniquet in the cementation quality (p value > 0.05). There was no difference between groups regarding gender, age, knee side, Visual VAS, Oxford Score, total range-of-motion (ROM), knee extension and knee flexion (p value > 0.05). CONCLUSIONS: No difference was attained regarding functional outcomes and cementation quality regarding two different tourniquet protocols.

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Relato sobre proposta inovadora, que se sustenta como ato terapêutico, lúdico e sequencial, objetivando encontros específicos para trabalhar de maneira psicoterápica questões ligadas às vidas e identidades, inclusive de gênero, dessas crianças. Em 2019, os pacientes de até 12 anos do Ambulatório Transdisciplinar de Identidade de Gênero e Orientação Sexual (AMTIGOS) do IPq/HC/FM/USP foram convidados a participar do Grupo de brincar. O grupo foi acompanhado por uma equipe transdisciplinar e mediado por psicólogos que apresentaram atividades estruturadas de forma a favorecer a explosão por parte das crianças e compartilhamento de suas experiências de forma lúdica.

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Abstract: Introduction: Human Rights are inherent to the human condition, considering all aspects of life: the right to life, to an education, to freedom, to religion, to security and to work. Given that, it is important to nurture a Human Rights culture in educational institutions, aiming at improving inter-personal dynamics and the educational environment. The tutors' development, in this aspect, becomes fundamental. Objective: To understand the meanings attributed by tutors to their experiences involving Human Rights situations in the academic environment as the first step to implement teacher development in this area. Methods: qualitative study involving tutors from a college located in northeastern Brazil, which employs the Problem-Based Learning methodology, between December of 2019 and September of 2020. The collection was performed through focal groups with intentional selection. The script for the discussion was based in the National Plan for Human Rights Education, The Human Rights Education Manual, The Universal Human Rights Declaration and articles related to the discussion topic. Bardin content analysis was used. The project was approved by the Ethics Committee under CAAE number 22696919.3.0000.5569. Results: The studied analytic categories were: gender and sexuality, communication and freedom of speech, social minorities and student self-esteem and stigmatization. During the process of reinterpreting the collected content, the following empirical subcategories were identified: ableism, fatphobia, psychophobia and interpersonal conflicts. The tutors revealed having experienced conflicts involving Human Rights, as follows: gender oppression; homophobia by students and teachers; lack of racial representativeness among the college student population; fatphobia in the academic environment; decrease in student's performance due to mental health issues. The participant tutors also expressed insecurity when it came to intervening and giving feedback in such situations, as well as some lack of knowledge about Human Rights. Conclusion: The tutors reported episodes that demonstrated Human Rights violation practices in the academic environment and showed to be insecure about intervening in such situations, especially when these situations led to conflict between the students.

Resumo: Introdução: Os direitos humanos (DH) são inerentes à condição humana, considerando todos os aspectos da vida: o direito à vida, à educação, à liberdade, à religião, à segurança e ao trabalho. Dessa forma, é importante incentivar a cultura dos DH nas instituições de ensino, na intenção de qualificar as dinâmicas interpessoais e o ambiente educacional. O desenvolvimento docente nesse aspecto torna-se fundamental. Objetivo: Este estudo teve como objetivo compreender os significados atribuídos pelos tutores às vivências envolvendo DH no ambiente acadêmico como primeiro passo para instituir o desenvolvimento docente nessa área. Método: Trata-se de um estudo qualitativo, realizado entre dezembro de 2019 e setembro de 2020, que envolveu tutores de uma faculdade do Nordeste do Brasil cuja metodologia de ensino é a Aprendizagem Baseada em Problemas. A coleta se deu por meio de grupos focais com seleção intencional. O roteiro para a discussão foi baseado no Plano Nacional de Educação em Direitos Humanos, no Caderno de Educação em Direitos Humanos, na Declaração de Direitos Humanos e em artigos referentes ao tema. Utilizou-se a análise de conteúdo de Bardin. O projeto recebeu parecer favorável do Comitê de Ética em Pesquisa: CAAE nº 22696919.3.0000.5569. Resultado: As categorias analíticas estudadas foram: gênero e sexualidade, comunicação e liberdade de expressão, minorias sociais e estigmatização e autoestima do estudante. Durante o processo de reinterpretação das falas, identificaram-se as seguintes subcategorias empíricas: capacitismo, gordofobia, saúde mental, psicofobia e conflitos interpessoais. Os docentes revelaram conflitos envolvendo DH, a exemplo das seguintes situações: opressão de gênero; homofobia por parte de docentes e estudantes; falta de representatividade racial na faculdade; gordofobia no ambiente acadêmico; queda de rendimento de estudantes por problemas de saúde mental. Expressaram insegurança em intervir e dar feedback em tais situações, bem como certo desconhecimento relacionado aos DH. Conclusão: Os docentes relataram episódios que demonstram práticas de violação aos DH no ambiente acadêmico e se mostraram inseguros para intervir nessas situações, sobretudo quando geravam conflito entre os estudantes.

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Este artigo apresenta os resultados de uma escuta clínica do sofrimento no trabalho com um grupo de servidores públicos federais. O aporte teórico é da Psicodinâmica do Trabalho e o percurso metodológico centra-se na construção de um espaço de discussão proposto pela prática clínica, com uso dos seguintes dispositivos: análise da demanda, transferência e interpretação; formação do clínico e supervisão clínica. Objetiva-se analisar as narrativas dos participantes por meio de uma pesquisa qualitativa de caráter descritivo. Foram realizadas 12 sessões com a participação de 11 servidores. Conclui-se que o uso dos dispositivos clínicos permitiu que os serv(i)dores mudassem suas atitudes frente ao trabalho, visto que atribuíram novos sentidos ao trabalho, (re)significando, assim, os conteúdos que desencadearam sofrimento intenso. Desse modo, percebeu-se que houve uma reorganização do sistema defensivo. Confirma-se, assim, a importância da clínica como potencial político de organização coletiva.

This article presents the results of clinical listening to suffering at work with a group of federal civil servants. The theoretical contribution comes from Psychodynamics of Work and the methodological approach focuses on the construction of a space for discussion as proposed by clinical practice, using the following devices: demand analysis, transference and interpretation; clinician training and clinical supervision. The objective is to analyze the participants' narratives through qualitative research and descriptive perspective. Twelve sessions were held with the participation of eleven civil servants. It is concluded that the use of clinical devices allowed civil servants to change their attitudes towards work, as they attributed new meanings to work, thus (re)signifying the contents that triggered intense suffering. Thus, it was noticed that there was a reorganization of the defensive system, and the importance of the clinic as a political potential for collective organization is confirmed.

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OBJECTIVE: To assess the number of cases and the profile of hospitalizations from varicella after the introduction of the measles, mumps, rubella and varicella combination vaccine in the public health system. METHODS: Retrospective study in an infectious diseases pediatric hospital of reference in Southeast Brazil. The cases with a clinical diagnosis of varicella, from January 2011 to June 2016, were assessed from pediatricians' medical records. The hospitalizations were classified into a pre-vaccine group and post-vaccine group, based on the date the vaccine was introduced (September 2013). Both groups were compared by age, sex, time of hospitalization, reason for hospitalization, hospital complications, duration of intensive care, and clinical outcome. RESULTS: A total of 830 hospitalizations were recorded; 543 in the pre-vaccine period and 287 in the post-vaccine period, a reduction of 47.1% (p<0.001). In both periods, a similar profile in the hospitalizations was noticed: majority male; aged between one to five years old; most complications due to secondary causes (mainly skin infections); main outcome was clinical improvement and discharge from the hospital. In the pre-vaccine period, six deaths were recorded and two were recorded in the post-vaccine period. CONCLUSIONS: The profile of the hospitalizations was expected to stay the same since this study did not compare vaccinated with unvaccinated children, but hospitalizations before and after the vaccine was introduced. In accordance with the medical literature, we found a significant fall in the number of hospitalizations from varicella.

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