RESUMEN
The clinical characteristics, pathological subtypes and patients' survival in 40 patients with thyroid carcinoma between March 2007 and March 2012 were evaluated. This study included 33 (82.5 %) females and seven (17.5%) males (female to male ratio of 4.7:1). The median age of patients was 47.5 (range; 24-64). Papillary carcinoma was the commonest pathological subtype (23 patients, 57.5%), followed by follicular carcinoma (14 patients, 35%) and medullary carcinoma (3 cases, 7.5%). Total thryoidectomy was performed in 30 (75%), lobectomy in six (15%), subtotal and multifocal thryoidectomy in two (5%) patients. The median time of follow up was 3 years with range of 1-5 years. After ive years 34 (85%) patients were alive and six (15%) were dead. The overall 5-year actuarial survival was 85%, for papillary carcinoma 91.3%, for follicular carcinoma 85.7% and for medullary carcinoma it was 33.3%. The results suggest that total thryoidectomy had better outcome in comparison with other surgeries.
Asunto(s)
Adenocarcinoma Folicular/cirugía , Neoplasias de la Tiroides/cirugía , Tiroidectomía , Adenocarcinoma Folicular/diagnóstico , Adenocarcinoma Folicular/epidemiología , Adulto , Carcinoma Neuroendocrino/cirugía , Carcinoma Papilar Folicular/cirugía , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Irán/epidemiología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Riesgo , Distribución por Sexo , Neoplasias de la Tiroides/diagnóstico , Neoplasias de la Tiroides/epidemiología , Tiroidectomía/métodos , Resultado del TratamientoRESUMEN
AIM: To investigate the impact of sex on white blood cells count after gastrectomy in patients with gastric cancer. METHODS: The study population included 48 patients who underwent total or subtotal gastrectomy for gastric cancer. Total white blood cells, neutrophils and lymphocytes counts of pre and postoperative day 1, 3, and 5 were reviewed from hospital database from 15 March 2009 to 1 December 2011 retrospectively. RESULTS: This investigation involved 28 male patients (58.33%) and 20 female patients (41.66%). The mean age of male and female patients was 69.4±14.2 and 65.2±15.6 year. There was a significant change in total white blood cells counts in post-operative day 3 (p= 0.041) and post-operative day 5 (p= 0.022) between males and females. Significant change was noted in post-operative day 5 for lymphocytes counts (p= 0.049). Neutrophil values indicated significant alterations in all pre and post gastrectomy days; pre-operative (p= 0.039), post-operative day 1 (p= 0.034), post-operative day 3 (p= 0.012), post-operative day 5 (p= 0.0102). CONCLUSION: In this comparison between genders, there was a significantly increased proportion of total white blood cells, neutrophils and lymphocytes in female subjects than in male individuals following gastrectomy. Our results revealed that female patients indicated more immune reactions to surgery than male patients. This research provided evidences that gender affects the cellular immunity after surgical stress.