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1.
J Theor Biol ; 433: 73-84, 2017 11 21.
Artículo en Inglés | MEDLINE | ID: mdl-28844907

RESUMEN

Proper design of stent for application at specific aneurysm effect arteries could help to reduce the issues with thrombosis and aneurysm. In this paper, four types of stent configuration namely half-Y (6 mm), half-Y (4 mm), cross-bar, and full-Y configuration will implanted on real 3D artery bifurcation aneurysm effected arteries. Comparisons were then conducted based on the flow patterns after stent placement using both LBM-based solver and PIV experimental findings. According to the data obtained from all 4 stent designs, the flow profiles and the computed velocity from both methods were in agreement with each other. Both methods found that half-Y (6 mm) stent configuration is by far the best configuration in reducing the blood velocity at the vicinity of the aneurysm sac. The analysis also show that the half-Y (6 mm) stent configuration recorded the highest percentage of velocity reduction and managed to substantially reduce the pressure at the bifurcation region. This high flow velocity reduction through the use of half-Y stent could consequently promote the formation of thrombus thereby reducing the risk of rupture in the aneurysm sac.


Asunto(s)
Aneurisma/terapia , Diseño de Equipo/métodos , Stents/normas , Velocidad del Flujo Sanguíneo , Prótesis Vascular , Simulación por Computador , Humanos , Modelos Cardiovasculares , Reología
2.
PLoS One ; 11(7): e0159357, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27454872

RESUMEN

This paper studies the three dimensional (3D) simulation of fluid flows through the ball grid array (BGA) to replicate the real underfill encapsulation process. The effect of different solder bump arrangements of BGA on the flow front, pressure and velocity of the fluid is investigated. The flow front, pressure and velocity for different time intervals are determined and analyzed for potential problems relating to solder bump damage. The simulation results from Lattice Boltzmann Method (LBM) code will be validated with experimental findings as well as the conventional Finite Volume Method (FVM) code to ensure highly accurate simulation setup. Based on the findings, good agreement can be seen between LBM and FVM simulations as well as the experimental observations. It was shown that only LBM is capable of capturing the micro-voids formation. This study also shows an increasing trend in fluid filling time for BGA with perimeter, middle empty and full orientations. The perimeter orientation has a higher pressure fluid at the middle region of BGA surface compared to middle empty and full orientation. This research would shed new light for a highly accurate simulation of encapsulation process using LBM and help to further increase the reliability of the package produced.


Asunto(s)
Modelos Teóricos , Algoritmos , Simulación por Computador
3.
Comput Math Methods Med ; 2016: 6143126, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27239221

RESUMEN

This paper simulates and predicts the laminar flow inside the 3D aneurysm geometry, since the hemodynamic situation in the blood vessels is difficult to determine and visualize using standard imaging techniques, for example, magnetic resonance imaging (MRI). Three different types of Lattice Boltzmann (LB) models are computed, namely, single relaxation time (SRT), multiple relaxation time (MRT), and regularized BGK models. The results obtained using these different versions of the LB-based code will then be validated with ANSYS FLUENT, a commercially available finite volume- (FV-) based CFD solver. The simulated flow profiles that include velocity, pressure, and wall shear stress (WSS) are then compared between the two solvers. The predicted outcomes show that all the LB models are comparable and in good agreement with the FVM solver for complex blood flow simulation. The findings also show minor differences in their WSS profiles. The performance of the parallel implementation for each solver is also included and discussed in this paper. In terms of parallelization, it was shown that LBM-based code performed better in terms of the computation time required.


Asunto(s)
Aneurisma/fisiopatología , Enfermedades de las Arterias Carótidas/fisiopatología , Imagenología Tridimensional/métodos , Anciano , Algoritmos , Velocidad del Flujo Sanguíneo , Simulación por Computador , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Presión , Prevalencia , Resistencia al Corte , Programas Informáticos , Estrés Mecánico
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