RESUMEN

Two dimeric steroidal terephthalates derived from epimeric 4,5-seco-cholest-3-yn-5-ols were prepared starting from cholesterol in a five-step synthetic sequence. X-ray crystallography shows that the obtained compounds display novel supramolecular networks in the solid state in which the facial hydrophobicity of the steroidal skeletons plays an important role. Unambiguous NMR characterization of the obtained dimers is also provided.

Asunto(s)

Colesterol/química , Dimerización , Ácidos Ftálicos/química , Ácidos Ftálicos/síntesis química , Técnicas de Química Sintética , Cristalografía por Rayos X , Espectroscopía de Resonancia Magnética , Modelos Moleculares , Conformación Molecular , Estereoisomerismo